Jan P Dumanski
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Explore the profile of Jan P Dumanski including associated specialties, affiliations and a list of published articles.
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83
Citations
2401
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Recent Articles
1.
Jakalski M, Bruhn-Olszewska B, Rychlicka-Buniowska E, Davies H, Sarkisyan D, Siedlar M, et al.
Cell Mol Life Sci
. 2025 Feb;
82(1):93.
PMID: 39998604
Alzheimer's disease (AD) is a common and increasing societal problem due to the extending human lifespan. In males, loss of chromosome Y (LOY) in leukocytes is strongly associated with AD....
2.
Bruhn-Olszewska B, Markljung E, Rychlicka-Buniowska E, Sarkisyan D, Filipowicz N, Dumanski J
Nat Rev Genet
. 2025 Jan;
PMID: 39743536
Loss of Y chromosome (LOY) is the most commonly occurring post-zygotic (somatic) mutation in male individuals. The past decade of research suggests that LOY has important effects in shaping the...
3.
Urbiola-Salvador V, Jablonska A, Miroszewska D, Kamysz W, Duzowska K, Drezek-Chyla K, et al.
Biomark Insights
. 2024 Jun;
19:11772719241257739.
PMID: 38911905
Background: Colorectal cancer (CRC) prognosis is determined by the disease stage with low survival rates for advanced stages. Current CRC screening programs are mainly using colonoscopy, limited by its invasiveness...
4.
Andreou M, Jakalski M, Duzowska K, Filipowicz N, Kostecka A, Davies H, et al.
Int J Cancer
. 2024 Jun;
155(9):1616-1628.
PMID: 38850108
Despite advances in early detection and treatment strategies, breast cancer recurrence and mortality remain a significant health issue. Recent insights suggest the prognostic potential of microscopically healthy mammary gland, in...
5.
Wojcik M, Juhas U, Mohammadi E, Mattisson J, Drezek-Chyla K, Rychlicka-Buniowska E, et al.
Sci Rep
. 2024 Apr;
14(1):9458.
PMID: 38658633
Male sex is a risk factor for colorectal cancer (CRC) with higher illness burden and earlier onset. Thus, we hypothesized that loss of chromosome Y (LOY) in the tumor micro-environment...
6.
Stankowska W, Sarkisyan D, Bruhn-Olszewska B, Duzowska K, Bienkowski M, Jakalski M, et al.
Cancers (Basel)
. 2024 Mar;
16(5).
PMID: 38473323
Bladder urothelial carcinoma (BLCA) is the 10th most common cancer with a low survival rate and strong male bias. We studied the field cancerization in BLCA using multi-sample- and multi-tissue-per-patient...
7.
Mattisson J, Halvardson J, Davies H, Bruhn-Olszewska B, Olszewski P, Danielsson M, et al.
BMC Genomics
. 2024 Mar;
25(1):243.
PMID: 38443832
Background: Mosaic loss of chromosome Y (LOY) in leukocytes is the most prevalent somatic aneuploidy in aging humans. Men with LOY have increased risks of all-cause mortality and the major...
8.
Dorvall M, Pedersen A, Dumanski J, Soderholm M, Lindgren A, Stanne T, et al.
Stroke
. 2023 Jul;
54(9):2434-2437.
PMID: 37465995
Background: Mosaic loss of chromosome Y (LOY) is associated with cardiovascular and neurodegenerative diseases in men, and genetic predisposition to LOY is associated with poor poststroke outcome. We, therefore, tested...
9.
Urbiola-Salvador V, Jablonska A, Miroszewska D, Huang Q, Duzowska K, Drezek-Chyla K, et al.
Front Oncol
. 2023 May;
13:1158261.
PMID: 37228491
Introduction: Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of death worldwide. Efficient non-invasive blood-based biomarkers for CRC early detection and prognosis are urgently...
10.
Mohammadi E, Chojnowska K, Bienkowski M, Kostecka A, Koczkowska M, Zmijewski M, et al.
J Transl Med
. 2023 Apr;
21(1):270.
PMID: 37081484
Background: Visium Spatial Gene Expression (ST) is a method combining histological spatial information with transcriptomics profiles directly from tissue sections. The use of spatial information has made it possible to...