Jan Lipfert
Overview
Explore the profile of Jan Lipfert including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
99
Citations
2617
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Chen L, Jager M, Rebergen D, Brink G, Ende T, Vanderlinden W, et al.
Genome Res
. 2025 Jan;
PMID: 39805703
Shallow genome-wide cell-free DNA (cfDNA) sequencing holds great promise for non-invasive cancer monitoring by providing reliable copy number alteration (CNA) and fragmentomic profiles. Single nucleotide variations (SNVs) are, however, much...
2.
Stubhan S, Baptist A, Korosy C, Narducci A, Moya Munoz G, Wendler N, et al.
Nanoscale
. 2024 Dec;
17(6):3322-3330.
PMID: 39691975
Biomolecular structures are typically determined using frozen or crystalline samples. Measurement of intramolecular distances in solution can provide additional insights into conformational heterogeneity and dynamics of biological macromolecules and their...
3.
Pritzl S, Ulugol A, Korosy C, Filion L, Lipfert J
Biophys J
. 2024 Oct;
123(22):3964-3976.
PMID: 39473184
Single-molecule force spectroscopy (SMFS) techniques play a pivotal role in unraveling the mechanics and conformational transitions of biological macromolecules under external forces. Among these techniques, multiplexed magnetic tweezers (MT) are...
4.
Exploring protein-mediated compaction of DNA by coarse-grained simulations and unsupervised learning
de Jager M, Kolbeck P, Vanderlinden W, Lipfert J, Filion L
Biophys J
. 2024 Jul;
123(18):3231-3241.
PMID: 39044429
Protein-DNA interactions and protein-mediated DNA compaction play key roles in a range of biological processes. The length scales typically involved in DNA bending, bridging, looping, and compaction (≥1 kbp) are...
5.
Lin Y, Muller P, Karagianni E, Hepp N, Mueller-Planitz F, Vanderlinden W, et al.
J Mol Biol
. 2024 Jun;
436(16):168671.
PMID: 38908785
Nucleosomes are the basic compaction unit of chromatin and nucleosome structure and their higher-order assemblies regulate genome accessibility. Many post-translational modifications alter nucleosome dynamics, nucleosome-nucleosome interactions, and ultimately chromatin structure...
6.
Lak A, Wang Y, Kolbeck P, Pauer C, Chowdhury M, Cassani M, et al.
Nanoscale
. 2024 Mar;
16(15):7678-7689.
PMID: 38533617
Magnetic nanoparticles (MNPs) provide new opportunities for enzyme-free biosensing of nucleic acid biomarkers and magnetic actuation by patterning on DNA origami, yet how the DNA grafting density affects their dynamics...
7.
Dohnalova H, Seifert M, Matouskova E, Klein M, Papini F, Lipfert J, et al.
J Phys Chem B
. 2024 Jan;
128(3):664-675.
PMID: 38197365
RNA plays critical roles in the transmission and regulation of genetic information and is increasingly used in biomedical and biotechnological applications. Functional RNAs contain extended double-stranded regions, and the structure...
8.
Bauer M, Gruber S, Hausch A, Melo M, Gomes P, Nicolaus T, et al.
Nat Nanotechnol
. 2023 Nov;
19(3):399-405.
PMID: 38012274
Mutations in SARS-CoV-2 have shown effective evasion of population immunity and increased affinity to the cellular receptor angiotensin-converting enzyme 2 (ACE2). However, in the dynamic environment of the respiratory tract,...
9.
Kolbeck P, Tisma M, Analikwu B, Vanderlinden W, Dekker C, Lipfert J
Nucleic Acids Res
. 2023 Nov;
52(1):59-72.
PMID: 38000393
DNA stores our genetic information and is ubiquitous in applications, where it interacts with binding partners ranging from small molecules to large macromolecular complexes. Binding is modulated by mechanical strains...
10.
Lin Y, Brouns T, Kolbeck P, Vanderlinden W, Lipfert J
J Biol Chem
. 2023 May;
299(7):104874.
PMID: 37257819
Force and torque spectroscopy have provided unprecedented insights into the mechanical properties, conformational transitions, and dynamics of DNA and DNA-protein complexes, notably nucleosomes. Reliable single-molecule manipulation measurements require, however, specific...