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Jan Kosla

Explore the profile of Jan Kosla including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 682
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Recent Articles
11.
Lounkova A, Kosla J, Prikryl D, Stafl K, Kucerova D, Svoboda J
Proc Natl Acad Sci U S A . 2017 Jun; 114(26):E5148-E5157. PMID: 28607078
The extent of virus transmission among individuals and species is generally determined by the presence of specific membrane-embedded virus receptors required for virus entry. Interaction of the viral envelope glycoprotein...
12.
Starostova M, cermak V, Dvorakova M, Karafiat V, Kosla J, Dvorak M
Gene . 2014 Mar; 540(1):122-9. PMID: 24576577
The neural crest (NC) is a transient dynamic structure of ectodermal origin, found in early vertebrate embryos. The multipotential NC cells migrate along well defined routes, differentiate to various cell...
13.
Kosla J, Dvorakova M, Dvorak M, cermak V
Eur J Cell Biol . 2013 Dec; 92(12):363-73. PMID: 24315689
Fibrotic diseases are a group of pathologies with high incidence and mortality. Despite extensive research efforts, effective therapies are still not available. Understanding the molecular mechanisms driving the onset, progression...
14.
Kovarova D, Plachy J, Kosla J, Trejbalova K, cermak V, Hejnar J
Mol Cancer Res . 2013 Aug; 11(10):1235-47. PMID: 23938949
Unlabelled: Comparing the gene expression profiles of metastatic and nonmetastatic cells has the power to reveal candidate metastasis-associated genes, whose involvement in metastasis can be experimentally tested. In this study,...
15.
Kosla J, Pankova D, Plachy J, Tolde O, Bicanova K, Dvorak M, et al.
Cell Commun Signal . 2013 Aug; 11:51. PMID: 23899007
Background: Although there is extensive evidence for the amoeboid invasiveness of cancer cells in vitro, much less is known about the role of amoeboid invasiveness in metastasis and the importance...
16.
Kosla J, Dvorak M, cermak V
Gene . 2012 Nov; 513(1):90-100. PMID: 23127594
The myofibroblast is a mesenchymal cell characterized by synthesis of the extracellular matrix, plus contractile and secretory activities. Myofibroblasts participate in physiological tissue repair, but can also cause devastating fibrosis....
17.
cermak V, Kosla J, Plachy J, Trejbalova K, Hejnar J, Dvorak M
Cell Mol Life Sci . 2010 May; 67(20):3557-68. PMID: 20505979
Metastatic spreading of cancer cells is a highly complex process directed primarily by the interplay between tumor microenvironment, cell surface receptors, and actin cytoskeleton dynamics. To advance our understanding of...