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James U Bowie

Explore the profile of James U Bowie including associated specialties, affiliations and a list of published articles. Areas
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Articles 116
Citations 4923
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Recent Articles
1.
Aoki M, Vinokur J, Motoyama K, Ishikawa R, Collazo M, Cascio D, et al.
J Biol Chem . 2022 Jun; 298(7):102111. PMID: 35690147
Mevalonate 3,5-bisphosphate decarboxylase is involved in the recently discovered Thermoplasma-type mevalonate pathway. The enzyme catalyzes the elimination of the 3-phosphate group from mevalonate 3,5-bisphosphate as well as concomitant decarboxylation of...
2.
Liu H, Arbing M, Bowie J
Sci Rep . 2022 May; 12(1):7700. PMID: 35546163
Ethanol is a widely available carbon compound that can be increasingly produced with a net negative carbon balance. Carbon-negative ethanol might therefore provide a feedstock for building a wider range...
3.
Corin K, Bowie J
EMBO Rep . 2022 Feb; 23(3):e53025. PMID: 35133709
Protein folding is a fundamental process of life with important implications throughout biology. Indeed, tens of thousands of mutations have been associated with diseases, and most of these mutations are...
4.
Liu H, Bowie J
Sci Rep . 2021 May; 11(1):9449. PMID: 33941811
It is now possible to efficiently fix flue gas CO/CO into ethanol using acetogens, thereby making carbon negative ethanol. While the ethanol could be burned as a fuel, returning the...
5.
Corin K, Bowie J
Protein Sci . 2020 Oct; 29(12):2348-2362. PMID: 33058341
The question of how proteins manage to organize into a unique three-dimensional structure has been a major field of study since the first protein structures were determined. For membrane proteins,...
6.
Sherkhanov S, Korman T, Chan S, Faham S, Liu H, Sawaya M, et al.
Nat Commun . 2020 Aug; 11(1):4292. PMID: 32855421
Cost competitive conversion of biomass-derived sugars into biofuel will require high yields, high volumetric productivities and high titers. Suitable production parameters are hard to achieve in cell-based systems because of...
7.
Valliere M, Korman T, Arbing M, Bowie J
Nat Chem Biol . 2020 Aug; 16(12):1427-1433. PMID: 32839605
Moving cannabinoid production away from the vagaries of plant extraction and into engineered microbes could provide a consistent, purer, cheaper and environmentally benign source of these important therapeutic molecules, but...
8.
Bowie J, Sherkhanov S, Korman T, Valliere M, Opgenorth P, Liu H
Trends Biotechnol . 2020 Jan; 38(7):766-778. PMID: 31983463
Metabolic engineering efforts that harness living organisms to produce natural products and other useful chemicals face inherent difficulties because the maintenance of life processes often runs counter to our desire...
9.
Choi H, Min D, Kang H, Shon M, Rah S, Kim H, et al.
Science . 2019 Nov; 366(6469):1150-1156. PMID: 31780561
To understand membrane protein biogenesis, we need to explore folding within a bilayer context. Here, we describe a single-molecule force microscopy technique that monitors the folding of helical membrane proteins...
10.
Valliere M, Korman T, Woodall N, Khitrov G, Taylor R, Baker D, et al.
Nat Commun . 2019 May; 10(1):2363. PMID: 31127097
In the original version of this Article, the genotype of the M30 mutant presented in Fig. 3b was given incorrectly as Y288V/A232S, and the M31 mutant was given incorrectly as...