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Duan Yang

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Articles 9
Citations 508
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Recent Articles
1.
Jia S, Yang X, Yang D, Wang R, Yang X, Huang M, et al.
BMC Cancer . 2025 Feb; 25(1):377. PMID: 40022054
Background: To investigate potential predictive factors and assess the utility of systemic inflammatory and nutritional indexes as prognostic indicators for survival in patients with FIGO stage III-IVA squamous cervical cancer...
2.
Zhang J, Zhang J, Wang Y, Sun Y, Wang Y, Wang Y, et al.
NPJ Vaccines . 2024 Oct; 9(1):196. PMID: 39443512
Hemorrhagic fever with renal syndrome (HFRS) occurs throughout Eurasia with considerable morbidity and mortality. Currently, the absence of specific treatments or effective antiviral drugs for hantavirus infection makes developing safe...
3.
Pu H, Chen Y, Shen R, Zhang Y, Yang D, Liu L, et al.
World J Surg Oncol . 2023 Apr; 21(1):137. PMID: 37101165
Background & Aims: In this retrospective study, we aimed to elucidate how the initial recurrence site influences the post-recurrence survival (PRS) after the curative resection of colorectal cancer. Patients And...
4.
Joh N, Oberai A, Yang D, Whitelegge J, Bowie J
J Am Chem Soc . 2009 Jul; 131(31):10846-7. PMID: 19603754
A major driving force for water-soluble protein folding is the hydrophobic effect, but membrane proteins cannot make use of this stabilizing contribution in the apolar core of the bilayer. It...
5.
Joh N, Min A, Faham S, Whitelegge J, Yang D, Woods V, et al.
Nature . 2008 May; 453(7199):1266-70. PMID: 18500332
Understanding the energetics of molecular interactions is fundamental to all of the central quests of structural biology including structure prediction and design, mapping evolutionary pathways, learning how mutations cause disease,...
6.
Kim S, Jeon T, Oberai A, Yang D, Schmidt J, Bowie J
Proc Natl Acad Sci U S A . 2005 Sep; 102(40):14278-83. PMID: 16179394
We have observed a common sequence motif in membrane proteins, which we call a glycine zipper. Glycine zipper motifs are strongly overrepresented and conserved in membrane protein sequences, and mutations...
7.
Yohannan S, Yang D, Faham S, Boulting G, Whitelegge J, Bowie J
J Mol Biol . 2004 Aug; 341(1):1-6. PMID: 15312757
Proline residues are relatively common in transmembrane helices. This suggests that proline substitutions may be readily tolerated in membrane proteins, even though they invariably produce deviations from canonical helical structure....
8.
Yohannan S, Faham S, Yang D, Grosfeld D, Chamberlain A, Bowie J
J Am Chem Soc . 2004 Feb; 126(8):2284-5. PMID: 14982414
Hydrogen bonds involving a carbon donor are very common in protein structures, and energy calculations suggest that Calpha-H...O hydrogen bonds could be about one-half the strength of traditional hydrogen bonds....
9.
Yohannan S, Faham S, Yang D, Whitelegge J, Bowie J
Proc Natl Acad Sci U S A . 2004 Jan; 101(4):959-63. PMID: 14732697
One of the hallmarks of membrane protein structure is the high frequency of transmembrane helix kinks, which commonly occur at proline residues. Because the proline side chain usually precludes normal...
10.
Faham S, Yang D, Bare E, Yohannan S, Whitelegge J, Bowie J
J Mol Biol . 2003 Dec; 335(1):297-305. PMID: 14659758
The molecular forces that stabilize membrane protein structure are poorly understood. To investigate these forces we introduced alanine substitutions at 24 positions in the B helix of bacteriorhodopsin and examined...