James R Stringer
Overview
Explore the profile of James R Stringer including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
839
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Recent Articles
1.
Gandhi M, Evdokimova V, Cuenco K, Nikiforova M, Kelly L, Stringer J, et al.
Proc Natl Acad Sci U S A
. 2012 May;
109(24):9454-9.
PMID: 22645362
Double-strand DNA breaks (DSBs) are continuously induced in cells by endogenously generated free radicals and exogenous genotoxic agents such as ionizing radiation. DSBs activate the kinase activity in sensor proteins...
2.
Evdokimova V, Gandhi M, Rayapureddi J, Stringer J, Nikiforov Y
Endocr Relat Cancer
. 2012 Feb;
19(3):271-81.
PMID: 22323563
Ionizing radiation (IR) exposure increases the risk of thyroid cancer and other cancer types. Chromosomal rearrangements, such as RET/PTC, are characteristic features of radiation-associated thyroid cancer and can be induced...
3.
Nkinin S, Stringer J, Keely S, Setchell K, Giner J, Kaneshiro E
J Eukaryot Microbiol
. 2011 May;
58(4):383-92.
PMID: 21569162
Pneumocystis carinii is an unusual fungus that can cause pneumonitis in immunosuppressed laboratory rats. Reactions in sterol biosynthesis are attractive targets for development of antimycotic drugs. A key enzyme in...
4.
Cushion M, Keely S, Stringer J
Mycologia
. 2010 Dec;
96(3):429-38.
PMID: 21148866
Organisms in the genus Pneumocystis are fungi that reside in the lungs of mammals that can cause a lethal pneumonia once the hosts lose immune function. The genus Pneumocystis contains...
5.
Cushion M, Stringer J
Annu Rev Microbiol
. 2010 Jun;
64:431-52.
PMID: 20528694
Pneumocystis species are ascomycetous fungi that obligatorily dwell with no apparent ill effect in the lungs of normal mammals, but they become pathogenic when host defenses are compromised. Identified more...
6.
Keely S, Stringer J
BMC Genomics
. 2009 Aug;
10:367.
PMID: 19664205
Background: The relationship between the parasitic fungus Pneumocystis carinii and its host, the laboratory rat, presumably involves features that allow the fungus to circumvent attacks by the immune system. It...
7.
Deitsch K, Lukehart S, Stringer J
Nat Rev Microbiol
. 2009 Jun;
7(7):493-503.
PMID: 19503065
The complex relationships between infectious organisms and their hosts often reflect the continuing struggle of the pathogen to proliferate and spread to new hosts, and the need of the infected...
8.
Stringer J, Beard C, Miller R
Emerg Infect Dis
. 2009 Feb;
15(3):506.
PMID: 19239784
No abstract available.
9.
Gandhi M, Stringer J, Nikiforova M, Medvedovic M, Nikiforov Y
Genes Chromosomes Cancer
. 2008 Nov;
48(3):222-8.
PMID: 19025793
Chromosomal rearrangements in human cancers are of two types, interchromosomal, which are rearrangements that involve exchange between loci located on different chromosomes, and intrachromosomal, which are rearrangements that involve loci...
10.
Fischer J, Stringer J
Mutat Res
. 2008 Aug;
645(1-2):1-8.
PMID: 18708075
Loss of heterozygosity (LOH) in somatic cells can contribute to the genesis of cancer, but little is known about the frequency with which LOH occurs in normal cells of the...