James R Paulson
Overview
Explore the profile of James R Paulson including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
650
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Paulson J
Methods Mol Biol
. 2024 Nov;
2874:183-198.
PMID: 39614056
Treatments which inhibit or inactivate Cdk1/cyclin B in metaphase-arrested mammalian cells and budding yeast are described. These treatments induce the cells to exit mitosis and return to interphase, though without...
2.
Samejima K, Gibcus J, Abraham S, Cisneros-Soberanis F, Samejima I, Beckett A, et al.
bioRxiv
. 2024 Apr;
PMID: 38659940
During mitosis, interphase chromatin is rapidly converted into rod-shaped mitotic chromosomes. Using Hi-C, imaging, proteomics and polymer modeling, we determine how the activity and interplay between loop-extruding SMC motors accomplishes...
3.
Keaton J, Workman B, Xie L, Paulson J
Chromosome Res
. 2023 Sep;
31(3):27.
PMID: 37690059
We show that specific inactivation of the protein kinase Cdk1/cyclin B (Cdc28/Clb2) triggers exit from mitosis in the budding yeast Saccharomyces cerevisiae. Cells carrying the allele cdc28-as1, which makes Cdk1...
4.
Keaton J, Workman B, Xie L, Paulson J
Res Sq
. 2023 Apr;
PMID: 37090579
We show that inactivation of the protein kinase Cdk1/Cyclin B (Cdc28/Clb 2 in the budding yeast ) is not only for cells to leave mitosis, as is well known, but...
5.
Paulson J, Vander Mause E, Dillinger E, Luedeman M, Usman B
Chromosome Res
. 2022 Nov;
30(4):351-359.
PMID: 36399199
Histones H1 and H3 are highly phosphorylated in mitotic HeLa cells but are rapidly dephosphorylated by endogenous protein phosphatases during the isolation of metaphase chromosomes. We show that this dephosphorylation...
6.
Paulson J, Hudson D, Cisneros-Soberanis F, Earnshaw W
Semin Cell Dev Biol
. 2021 Apr;
117:7-29.
PMID: 33836947
Our understanding of the structure and function of mitotic chromosomes has come a long way since these iconic objects were first recognized more than 140 years ago, though many details...
7.
Saldivar J, Hamperl S, Bocek M, Chung M, Bass T, Cisneros-Soberanis F, et al.
Science
. 2018 Aug;
361(6404):806-810.
PMID: 30139873
The cell cycle is strictly ordered to ensure faithful genome duplication and chromosome segregation. Control mechanisms establish this order by dictating when a cell transitions from one phase to the...
8.
Samejima K, Booth D, Ogawa H, Paulson J, Xie L, Watson C, et al.
J Cell Sci
. 2018 Jan;
131(4).
PMID: 29361541
The requirement for condensin in chromosome formation in somatic cells remains unclear, as imperfectly condensed chromosomes do form in cells depleted of condensin by conventional methodologies. In order to dissect...
9.
Gibcus J, Samejima K, Goloborodko A, Samejima I, Naumova N, Nuebler J, et al.
Science
. 2018 Jan;
359(6376).
PMID: 29348367
Mitotic chromosomes fold as compact arrays of chromatin loops. To identify the pathway of mitotic chromosome formation, we combined imaging and Hi-C analysis of synchronous DT40 cell cultures with polymer...
10.
Zhang T, Paulson J, Bakhrebah M, Kim J, Nowell C, Kalitsis P, et al.
Chromosome Res
. 2016 Mar;
24(2):243-69.
PMID: 27008552
Condensin is an integral component of the mitotic chromosome condensation machinery, which ensures orderly segregation of chromosomes during cell division. In metazoans, condensin exists as two complexes, condensin I and...