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James R Hailey

Explore the profile of James R Hailey including associated specialties, affiliations and a list of published articles. Areas
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Citations 212
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Recent Articles
1.
Hailey J, Maleeff B, Thomas H, Pearse G, Klapwijk J, Cristofori P, et al.
Toxicol Pathol . 2017 Dec; 45(8):1055-1066. PMID: 29233079
To test the diagnostic approach described in part 1 of this article, 2 exercises were completed by pathologists from multiple companies/agencies. Pathologist's examination of whole slide image (WSI) heart sections...
2.
Hailey J, Maleeff B, Thomas H, Pearse G, Klapwijk J, Cristofori P, et al.
Toxicol Pathol . 2017 Nov; 45(8):1043-1054. PMID: 29173114
Spontaneous rodent progressive cardiomyopathy (PCM) in the Sprague Dawley rat may confound identification and/or interpretation of potential test article (TA)-related cardiotoxicity. Pathologists apply diagnostic term(s) and thresholds for diagnosing and...
3.
Elmore S, Farman C, Hailey J, Kovi R, Malarkey D, Morrison J, et al.
Toxicol Pathol . 2016 Apr; 44(4):502-35. PMID: 27075180
The 2015 Annual National Toxicology Program Satellite Symposium, entitled "Pathology Potpourri" was held in Minneapolis, Minnesota, at the American College of Veterinary Pathologists/American Society for Veterinary Clinical Pathology/Society of Toxicologic...
4.
Elmore S, Dixon D, Hailey J, Harada T, Herbert R, Maronpot R, et al.
Toxicol Pathol . 2016 Feb; 44(2):173-88. PMID: 26879688
Historically, there has been confusion relating to the diagnostic nomenclature for individual cell death. Toxicologic pathologists have generally used the terms "single cell necrosis" and "apoptosis" interchangeably. Increased research on...
5.
Weber K, Hailey J, Mann P, Seaton M, Funk K
Toxicol Pathol . 2014 Jan; 42(1):275. PMID: 24436040
This continuing education course presented at the Society of Toxicologic Pathology's 31st Annual Symposium explored and defined the many roles that toxicologic pathologists serve Good Laboratory Practice (GLP)-conducted toxicology and...
6.
Hailey J
Toxicol Pathol . 2013 Nov; 42(1):278-82. PMID: 24178581
While the study pathologist (SP) signs the pathology report and is ultimately accountable for the data, the sponsor peer review pathologist (SPRP) generally signs a peer review (PR) statement indicating...
7.
Hailey J, Nold J, Brown R, Cullen J, Holder J, Jordan H, et al.
Toxicol Pathol . 2013 Aug; 42(5):844-54. PMID: 23960163
Whether biliary proliferative lesions in nonclinical species are predictive of potential hepatotoxicity in humans depends, at least in part, on the nature and severity of such changes in the nonclinical...
8.
Stokes A, Kemp D, Faiola B, Jordan H, Merrill C, Hailey J, et al.
Int J Toxicol . 2013 Apr; 32(3):189-97. PMID: 23616145
When conventional vehicles (eg, methylcellulose and water) impart inadequate physical, chemical, and/or biological properties for proper toxicological assessment of test article formulations, nonconventional vehicles may be considered. Often toxicity data...
9.
Sistare F, Morton D, Alden C, Christensen J, Keller D, Jonghe S, et al.
Toxicol Pathol . 2011 Jun; 39(4):716-44. PMID: 21666103
Data collected from 182 marketed and nonmarketed pharmaceuticals demonstrate that there is little value gained in conducting a rat two-year carcinogenicity study for compounds that lack: (1) histopathologic risk factors...
10.
Bach U, Hailey J, Hill G, Kaufmann W, Latimer K, Malarkey D, et al.
Toxicol Pathol . 2009 Dec; 38(1):9-36. PMID: 20008954
The National Toxicology Program (NTP) Satellite Symposium is a one-day meeting that is held in conjunction with the annual Society of Toxicologic Pathology (STP) meeting. The topic of the 2009...