James P Garnett
Overview
Explore the profile of James P Garnett including associated specialties, affiliations and a list of published articles.
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29
Citations
695
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Recent Articles
1.
Powell J, Powell S, Mather M, Beck L, Nelson A, Palmowski P, et al.
Thorax
. 2023 Feb;
78(10):1019-1027.
PMID: 36808087
Background: Tracheostomies in children are associated with significant morbidity, poor quality of life, excess healthcare costs and excess mortality. The underlying mechanisms facilitating adverse respiratory outcomes in tracheostomised children are...
2.
Ahmed E, Fieldes M, Bourguignon C, Mianne J, Petit A, Jory M, et al.
Cells
. 2022 Aug;
11(15).
PMID: 35954266
Background: Chronic Obstructive Pulmonary Disease (COPD), a major cause of mortality and disability, is a complex disease with heterogeneous and ill-understood biological mechanisms. Human induced pluripotent stem cells (hiPSCs) are...
3.
Mumby S, Kermani N, Garnett J, Pavlidis S, Wilson S, Howarth P, et al.
Allergy
. 2022 Aug;
77(11):3463-3466.
PMID: 35916059
No abstract available.
4.
Cheng Y, Hall T, Xu X, Yung I, Souza D, Zheng J, et al.
EBioMedicine
. 2021 Dec;
75:103758.
PMID: 34933179
Background: Loss of intestinal epithelial barrier integrity is a critical component of Inflammatory Bowel Disease (IBD) pathogenesis. Co-expression regulation of ligand-receptor pairs in IBD mucosa has not been systematically studied....
5.
Hatton C, Botting R, Duenas M, Haq I, Verdon B, Thompson B, et al.
Nat Commun
. 2021 Dec;
12(1):7092.
PMID: 34876592
The nasal epithelium is a plausible entry point for SARS-CoV-2, a site of pathogenesis and transmission, and may initiate the host response to SARS-CoV-2. Antiviral interferon (IFN) responses are critical...
6.
Bluhmki T, Traub S, Muller A, Bitzer S, Schruf E, Bammert M, et al.
Sci Rep
. 2021 Aug;
11(1):17028.
PMID: 34426605
In order to circumvent the limited access and donor variability of human primary alveolar cells, directed differentiation of human pluripotent stem cells (hiPSCs) into alveolar-like cells, provides a promising tool...
7.
Le H, Hill M, Kollak I, Keck M, Schroeder V, Wirth J, et al.
EMBO Rep
. 2021 Jul;
22(8):e52785.
PMID: 34224201
Unveiling the molecular mechanisms of tissue remodelling following injury is imperative to elucidate its regenerative capacity and aberrant repair in disease. Using different omics approaches, we identified enhancer of zester...
8.
Schruf E, Schroeder V, Le H, Schonberger T, Raedel D, Stewart E, et al.
FASEB J
. 2020 Apr;
34(6):7825-7846.
PMID: 32297676
Idiopathic pulmonary fibrosis (IPF) is a fatal disease of unknown cause that is characterized by progressive fibrotic lung remodeling. An abnormal emergence of airway epithelial-like cells within the alveolar compartments...
9.
Mavin E, Verdon B, Carrie S, Saint-Criq V, Powell J, Kuttruff C, et al.
Am J Physiol Lung Cell Mol Physiol
. 2020 Apr;
318(6):L1158-L1164.
PMID: 32267720
Shifts in cellular metabolic phenotypes have the potential to cause disease-driving processes in respiratory disease. The respiratory epithelium is particularly susceptible to metabolic shifts in disease, but our understanding of...
10.
Bearham J, Garnett J, Schroeder V, Biggart M, Baines D
Am J Physiol Cell Physiol
. 2019 Aug;
317(5):C983-C992.
PMID: 31433692
The airway epithelium maintains differential glucose concentrations between the airway surface liquid (ASL, ~0.4 mM) and the blood/interstitium (5-6 mM), which is important for defense against infection. Glucose primarily moves...