Deborah L Baines
Overview
Explore the profile of Deborah L Baines including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
43
Citations
968
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Vasiljevs S, Witney A, Baines D
Am J Physiol Lung Cell Mol Physiol
. 2023 Dec;
326(2):L125-L134.
PMID: 38084404
Cystic fibrosis-related diabetes (CFRD) affects 40%-50% of adults with CF and is associated with a decline in respiratory health. The microbial flora of the lung is known to change with...
2.
Walker A, Graham C, Greenwood M, Woodall M, Maeshima R, OHara-Wright M, et al.
Mol Ther Methods Clin Dev
. 2023 Nov;
31:101140.
PMID: 38027060
Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the gene. The 10th most common mutation, c.3178-2477C>T (3849+10kb C>T), involves a cryptic, intronic splice site. This mutation...
3.
Kalsi K, Jackson S, Baines D
PLoS One
. 2023 Jul;
18(7):e0287183.
PMID: 37406028
Airway diseases can disrupt tight junction proteins, compromising the epithelial barrier and making it more permeable to pathogens. In people with pulmonary disease who are prone to infection with Pseudomonas...
4.
Wu T, Wrennall J, Dang H, Baines D, Tarran R
Cells
. 2023 Apr;
12(7).
PMID: 37048070
Primary human bronchial epithelial cultures (HBECs) are used to study airway physiology, disease, and drug development. HBECs often replicate human airway physiology/pathophysiology. Indeed, in the search for cystic fibrosis (CF)...
5.
Baines D, Vasiljevs S, Kalsi K
Am J Physiol Cell Physiol
. 2022 Nov;
324(1):C153-C166.
PMID: 36409177
New technologies such as single-cell RNA sequencing (scRNAseq) has enabled identification of the mRNA transcripts expressed by individual cells. This review provides insight from recent scRNAseq studies on the expression...
6.
Woodall M, Reidel B, Kesimer M, Tarran R, Baines D
Am J Physiol Cell Physiol
. 2021 Oct;
321(6):C954-C963.
PMID: 34613844
Airway secretions contain many signaling molecules and peptides/proteins that are not found in airway surface liquid (ASL) generated by normal human bronchial epithelial cells (NHBEs) in vitro. These play a...
7.
Bearham J, Krutrok N, Lindberg B, Woodall M, Astrand A, Taylor J, et al.
PLoS One
. 2021 Jul;
16(7):e0254248.
PMID: 34242292
We have modified the periplasmic Escherichia coli glucose/galactose binding protein (GBP) and labelled with environmentally sensitive fluorophores to further explore its potential as a sensor for the evaluation of glucose...
8.
Pan X, Phanish M, Baines D, Dockrell M
Biosci Rep
. 2021 May;
41(6).
PMID: 34003249
Background: In the kidney glucose is freely filtered by the glomerulus and, mainly, reabsorbed by sodium glucose cotransporter 2 (SGLT2) expressed in the early proximal tubule. Human proximal tubule epithelial...
9.
10.
Bearham J, Garnett J, Schroeder V, Biggart M, Baines D
Am J Physiol Cell Physiol
. 2019 Aug;
317(5):C983-C992.
PMID: 31433692
The airway epithelium maintains differential glucose concentrations between the airway surface liquid (ASL, ~0.4 mM) and the blood/interstitium (5-6 mM), which is important for defense against infection. Glucose primarily moves...