James Nadel
Overview
Explore the profile of James Nadel including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
66
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Recent Articles
1.
Nadel J, Rodriguez-Palomares J, Phinikaridou A, Prieto C, Masci P, Botnar R
J Cardiovasc Magn Reson
. 2025 Feb;
:101865.
PMID: 39986653
Thoracic aortopathies result in aneurysmal expansion of the aorta that can lead to rapidly fatal aortic dissection or rupture. Despite the availability of abundant non-invasive imaging tools, the greatest contemporary...
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Nadel J, Tumanov S, Kong S, Chen W, Giannotti N, Sivasubramaniam V, et al.
JACC Adv
. 2024 Jun;
2(3):100310.
PMID: 38939599
Background: The detection of unstable atherosclerosis remains elusive. Intraplaque myeloperoxidase (MPO) activity causes plaque destabilization in preclinical models, holding promise for clinical translation as a novel imaging biomarker. Objectives: The...
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Paratz E, Nadel J, Humphries J, Rowe S, Fahy L, La Gerche A, et al.
Eur Heart J Cardiovasc Imaging
. 2024 May;
25(10):1423-1431.
PMID: 38805749
Aims: Increasing aortic dilation increases the risk of aortic dissection. Nevertheless, dissection occurs at dimensions below guideline-directed cut-offs for prophylactic surgery. Currently, there are no large-scale population imaging data assessing...
6.
Nadel J, Wang X, Saha P, Bongers A, Tumanov S, Giannotti N, et al.
Eur Heart J Imaging Methods Pract
. 2024 Feb;
2(1):qyae004.
PMID: 38370393
Aims: Unstable atherosclerotic plaques have increased activity of myeloperoxidase (MPO). We examined whether molecular magnetic resonance imaging (MRI) of intraplaque MPO activity predicts future atherothrombosis in rabbits and correlates with...
7.
Li W, Lin A, Hutton M, Dhaliwal H, Nadel J, Rodor J, et al.
bioRxiv
. 2023 Oct;
PMID: 37873248
Atherosclerosis is a chronic inflammatory disease which is driven in part by the aberrant -differentiation of vascular smooth muscle cells (SMCs). No therapeutic drug has been shown to reverse detrimental...
8.
Chen W, Nadel J, Tumanov S, Stocker R
Int J Mol Sci
. 2023 Jul;
24(13).
PMID: 37445903
Near-infrared autofluorescence (NIRAF) in unstable atherosclerotic plaque has been suggested as a novel imaging technology for high-risk atherosclerosis. Intraplaque hemorrhage (IPH) and bilirubin, derived from the subsequent degradation of heme,...
9.
Nadel J, Giannotti N, Kong S, Ugander M, Jabbour A, Stocker R
J Cardiovasc Comput Tomogr
. 2023 Apr;
17(5):358-360.
PMID: 37032220
No abstract available.
10.
Chen W, Tumanov S, Stanley C, Kong S, Nadel J, Vigder N, et al.
Circ Res
. 2023 Mar;
132(7):812-827.
PMID: 36876485
Background: The rupture of atherosclerotic plaque contributes significantly to cardiovascular disease. Plasma concentrations of bilirubin-a byproduct of heme catabolism-inversely associate with risk of cardiovascular disease, although the link between bilirubin...