James N Tsoporis
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Explore the profile of James N Tsoporis including associated specialties, affiliations and a list of published articles.
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53
Citations
675
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Recent Articles
1.
Armyra K, Ektesabi A, Tsoporis J, Izhar S, Triantafyllis A, Leong-Poi H, et al.
Pharmacol Rep
. 2025 Mar;
PMID: 40085417
Background: In psoriasis, damage-associated molecular patterns (DAMPs) released by damaged local tissue act as danger signals and trigger inflammatory responses. Statins, in addition to cholesterol-lowering, have anti-inflammatory effects. We sought...
2.
Gupta S, Lopez M, Ektesabi A, Tsoporis J, Vaswani C, Gandhi S, et al.
Cells
. 2025 Feb;
14(4).
PMID: 39996713
The canonical function of caspase-8 is to control timely cellular apoptosis to maintain tissue homeostasis and clear dysfunctional cells; however, emerging findings reveal novel, non-canonical roles of caspase in addition...
3.
Kallinikas G, Haronis G, Kallinika E, Kozyrakis D, Rodinos E, Filios A, et al.
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39409033
Diabetic bladder dysfunction (DBD) comprises a wide spectrum of lower urinary tract symptoms that impact diabetic patients' lives, including urinary frequency, urgency, incontinence, and incomplete bladder emptying. To relieve symptoms,...
4.
Triantafyllis A, Sfantou D, Karapedi E, Peteinaki K, Kotoulas S, Saad R, et al.
Med Princ Pract
. 2024 Sep;
34(1):1-12.
PMID: 39307131
Patients with SARS-CoV-2 infection carry an increased risk of cardiovascular disease encompassing various implications, including acute myocardial injury or infarction, myocarditis, heart failure, and arrhythmias. A growing volume of evidence...
5.
Vaswani C, Simone J, Pavelick J, Wu X, Tan G, Ektesabi A, et al.
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38474059
Acute Respiratory Distress Syndrome (ARDS) is characterized by lung inflammation and increased membrane permeability, which represents the leading cause of mortality in ICUs. Mechanical ventilation strategies are at the forefront...
6.
Kallinikas G, Tsoporis J, Haronis G, Zarkadas A, Bozios D, Konstantinopoulos V, et al.
World J Urol
. 2024 Feb;
42(1):71.
PMID: 38315192
Purpose: A variety of pathologic conditions may increase oxidative stress in semen resulting in structural modifications to spermozoa's plasma membrane that interfere with sperm motility, morphology, and count. Antioxidants are...
7.
Tsoporis J, Triantafyllis A, Kalogeropoulos A, Izhar S, Rigopoulos A, Rallidis L, et al.
Biomolecules
. 2024 Jan;
14(1).
PMID: 38275751
Coronary artery ectasia (CAE) is defined as abnormal dilation of a coronary artery with a diameter exceeding that of adjacent normal arterial segment by >1.5 times. CAE is a pathological...
8.
Gkavogiannakis N, Tsoporis J, Drosatos I, Tsirebolos G, Izhar S, Sakadakis E, et al.
Biomolecules
. 2023 Jun;
13(6).
PMID: 37371535
Asthma is a heterogeneous disease, characterized by chronic inflammation and oxidative stress of the airways. Several inflammatory pathways including activation of the receptor for advanced glycation end products (RAGE) have...
9.
Vaswani C, Varkouhi A, Gupta S, Ektesabi A, Tsoporis J, Yousef S, et al.
Mol Ther
. 2023 Jun;
31(9):2681-2701.
PMID: 37340634
Virus-induced lung injury is associated with loss of pulmonary epithelial-endothelial tight junction integrity. While the alveolar-capillary membrane may be an indirect target of injury, viruses may interact directly and/or indirectly...
10.
Tsoporis J, Amatullah H, Gupta S, Izhar S, Ektesabi A, Vaswani C, et al.
Antioxidants (Basel)
. 2023 Mar;
12(3).
PMID: 36978809
Oxidative stress is considered one of the early underlying contributors of sepsis-induced myocardial depression. DJ-1, also known as PARK7, has a well-established role as an antioxidant. We have previously shown,...