James N Tsoporis
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Explore the profile of James N Tsoporis including associated specialties, affiliations and a list of published articles.
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53
Citations
675
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Recent Articles
11.
Tsirebolos G, Tsoporis J, Drosatos I, Izhar S, Gkavogiannakis N, Sakadakis E, et al.
Int J Cardiol
. 2023 Feb;
376:127-133.
PMID: 36758863
Background And Aims: The multi-ligand receptor for advanced glycation end products (RAGE) and its ligands AGEs and S100/calgranulin proteins are important mediators of inflammation and oxidative stress whereas the soluble...
12.
Efstathiou V, Stefanou M, Demetriou M, Siafakas N, Katsantoni E, Makris M, et al.
Exp Ther Med
. 2022 Nov;
24(5):705.
PMID: 36324612
The ongoing coronavirus disease 2019 (COVID-19) pandemic has had a widespread impact on individuals' mental health through indirect psychological and social mechanisms, related to factors such as fear of infection...
13.
Gupta S, Amatullah H, Tsoporis J, Wei K, Teixeira Monteiro A, Ektesabi A, et al.
Cell Death Differ
. 2022 May;
29(10):2024-2033.
PMID: 35641782
The ability to effectively clear infection is fundamental to host survival. Sepsis, defined as dysregulated host response to infection, is a heterogenous clinical syndrome that does not uniformly clear intact...
14.
Efstathiou V, Stefanou M, Demetriou M, Siafakas N, Makris M, Tsivgoulis G, et al.
Exp Ther Med
. 2022 May;
23(5):363.
PMID: 35493431
There is accumulating evidence in the literature indicating that a number of patients with coronavirus disease 2019 (COVID-19) may experience a range of neuropsychiatric symptoms, persisting or even presenting following...
15.
Tsoporis J, Ektesabi A, Gupta S, Izhar S, Salpeas V, Rizos I, et al.
J Psychiatr Res
. 2021 Dec;
146:109-117.
PMID: 34971908
Among different proposed pathophysiological mechanisms, redox imbalance has been suggested to be a potential contributor in the pathogenesis of schizophrenia. DJ-1 is a redox-sensitive protein that has been shown to...
16.
Drosatos I, Tsoporis J, Izhar S, Gupta S, Tsirebolos G, Sakadakis E, et al.
Biomolecules
. 2021 Sep;
11(9).
PMID: 34572568
Apart from its beneficial effects on cardiovascular risk factors, an anti-inflammatory effect of exercise is strongly implicated. Yet, data regarding the effect of an exercise intervention on healthy individuals are...
17.
Tsoporis J, Drosatos I, Gupta S, Amatullah H, Izhar S, Santos C, et al.
Molecules
. 2021 Jul;
26(13).
PMID: 34206441
DJ-1 was originally identified as an oncogene product while mutations of the gene encoding DJ-1/PARK7 were later associated with a recessive form of Parkinson's disease. Its ubiquitous expression and diversity...
18.
Santos C, Amatullah H, Vaswani C, Maron-Gutierrez T, Kim M, Mei S, et al.
Eur Respir J
. 2021 Jun;
59(1).
PMID: 34112731
Although mesenchymal stromal (stem) cell (MSC) administration attenuates sepsis-induced lung injury in pre-clinical models, the mechanism(s) of action and host immune system contributions to its therapeutic effects remain elusive. We...
19.
Varkouhi A, He X, Teixeira Monteiro A, Amatullah H, Tsoporis J, Gupta S, et al.
Exp Cell Res
. 2021 Jan;
399(2):112473.
PMID: 33428902
Sepsis is a complicated multi-system disorder characterized by a dysregulated host response to infection. Despite substantial progress in the understanding of mechanisms of sepsis, translation of these advances into clinically...
20.
Ektesabi A, Mori K, Tsoporis J, Vaswani C, Gupta S, Walsh C, et al.
Shock
. 2020 Dec;
56(1):133-141.
PMID: 33378320
Sepsis-induced myocardial dysfunction (MD) is an important pathophysiological feature of multiorgan failure caused by a dysregulated host response to infection. Patients with MD continue to be managed in intensive care...