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James N Fullerton

Explore the profile of James N Fullerton including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 1320
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Recent Articles
1.
Higham H, Morgan L, Cooper C, Marshall J, Mawer A, Jackson S, et al.
Br J Clin Pharmacol . 2023 Oct; 90(7):1586-1599. PMID: 37903635
Aims: The influence of human factors on safety in healthcare settings is well established, with targeted interventions reducing risk and enhancing team performance. In experimental and early phase clinical research...
2.
Shah R, Mentzer A, James T, Cox S, Paddon K, Bowen J, et al.
J Infect . 2023 Jan; 86(5):534-536. PMID: 36681156
No abstract available.
3.
Drennan P, Karponis D, Richards D, Coles M, Fullerton J
Clin Transl Sci . 2022 Nov; 16(3):357-382. PMID: 36420645
Experimental exposure of healthy volunteers to the T-cell dependent neoantigen keyhole limpet hemocyanin (KLH) permits the evaluation of immunomodulatory investigational medicinal product (IMP) pharmacology prior to the recruitment of patient...
4.
Mentzer A, James T, Yongya M, Cox S, Paddon K, Shine B, et al.
J Infect . 2021 Nov; 84(2):e27-e29. PMID: 34843810
No abstract available.
5.
Fullerton J, Della Pasqua O, Likic R
Br J Clin Pharmacol . 2020 Oct; 87(3):738-740. PMID: 33078437
No abstract available.
6.
Pritchard R, Zhukov A, Fullerton J, Want A, Hussain F, la Cour M, et al.
Lab Chip . 2019 Jun; 19(14):2456-2465. PMID: 31210196
The sorting of specific cell populations is an established tool in biological research, with new applications demanding greater cell throughput, sterility and elimination of cross-contamination. Here we report 'vortex-actuated cell...
7.
Patel A, Zhang Y, Fullerton J, Boelen L, Rongvaux A, Maini A, et al.
J Exp Med . 2017 Jun; 214(7):1913-1923. PMID: 28606987
In humans, the monocyte pool comprises three subsets (classical, intermediate, and nonclassical) that circulate in dynamic equilibrium. The kinetics underlying their generation, differentiation, and disappearance are critical to understanding both...
8.
Fullerton J, Thompson K, Shetty A, Iredell J, Lander H, Myburgh J, et al.
Crit Care Resusc . 2017 Feb; 19(1):9-13. PMID: 28215126
Objective: To estimate the impact of adopting the proposed new diagnostic criteria for sepsis, based on Sequential Organ Failure Assessment (SOFA) criteria, on the diagnosis and apparent mortality of sepsis...
9.
Motwani M, Flint J, De Maeyer R, Fullerton J, Smith A, Marks D, et al.
J Pathol Clin Res . 2016 Aug; 2(3):154-65. PMID: 27499924
Whilst numerous studies investigating the aetiology of inflammatory diseases have been performed in rodents, the applicability of these data to human pathophysiology is frequently debated. Regardless of the strengths and...
10.
Fullerton J, Segre E, De Maeyer R, Maini A, Gilroy D
J Vis Exp . 2016 May; (111). PMID: 27213711
Activation of inflammatory pathways represents a central mechanism in multiple disease states both acute and chronic. Triggered via either pathogen or tissue damage-associated molecular motifs, common biochemical pathways lead to...