James McNulty
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Explore the profile of James McNulty including associated specialties, affiliations and a list of published articles.
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88
Citations
608
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Recent Articles
1.
Kempthorne C, St Pierre M, Le A, Livingstone S, McNulty J, Cadotte M, et al.
Phytochemistry
. 2024 Mar;
221:114051.
PMID: 38452878
The genus Vincetoxicum includes a couple of highly invasive vines in North America that threaten biodiversity and challenge land management strategies. Vincetoxicum species are known to produce bioactive phenanthroindolizidine alkaloids...
2.
St Pierre M, Kempthorne C, Liscombe D, McNulty J
Org Biomol Chem
. 2023 Sep;
21(40):8075-8078.
PMID: 37665044
A rapid total synthesis of seco-phenanthroindolizidine alkaloids was achieved involving a one-pot acid catalyzed deprotection- condensation-electrocyclization strategy. This synthetic route provided a concise synthesis of (±)-seco-antofine and (±)-septicine in only...
3.
Kempthorne C, Borra S, Kumar M, Dokuburra C, Liscombe D, McNulty J
Nat Prod Res
. 2023 Feb;
37(24):4232-4238.
PMID: 36744673
Emerging buds of were found to accumulate the alkaloid haemanthamine () at high concentrations, exceeding that of narciclasine (), the most abundant constituent in bulbs of the plant. A phytoactivity...
4.
McNulty J, Babu-Dokuburra C, Scattolon J, Zepeda-Velazquez C, Wesesky M, Caldwell J, et al.
Sci Rep
. 2023 Jan;
13(1):1639.
PMID: 36717567
The total synthesis of four novel mono-methoxy and hydroxyl substituted ring-A dihydronarciclasine derivatives enabled identification of the 7-hydroxyl derivative as a potent and selective antiviral agent targeting SARSCoV-2 and HSV-1....
5.
Liscombe D, Kamiyoshihara Y, Ghironzi J, Kempthorne C, Hooton K, Bulot B, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(7).
PMID: 35131946
Tomato () produces a wide range of volatile chemicals during fruit ripening, generating a distinct aroma and contributing to the overall flavor. Among these volatiles are several aromatic and aliphatic...
6.
McNulty J, Millar M, Bernardinelli G, Jefford C
J Org Chem
. 2021 Jul;
64(14):5312-5314.
PMID: 34237843
No abstract available.
7.
Kempthorne C, Nielsen A, Wilson D, McNulty J, Cameron R, Liscombe D
Phytochemistry
. 2021 Apr;
187:112747.
PMID: 33823457
The leaf intercellular space is a site of plant-microbe interactions where pathogenic bacteria such as Pseudomonas syringae grow. In Arabidopsis thaliana, the biosynthesis of tryptophan-derived indolic metabolites is induced by...
8.
McNulty J, Dokuburra C, DAiuto L, Demers M, McClain L, Piazza P, et al.
Bioorg Med Chem Lett
. 2020 Sep;
30(24):127559.
PMID: 32961320
The synthesis of a lead anti-viral cyclopropyl carboxy acyl hydrazone 4F17 (5) and three sequential arrays of structural analogues along with the initial assessment and optimization of the antiviral pharmacophore...
9.
Wolford-Clevenger C, Hugley M, McNulty J, Elledge L, Cropsey K, Stuart G
Account Res
. 2019 Nov;
26(8):498-511.
PMID: 31738573
Ethics committee members and researchers have deliberated about the risk-benefit ratio of researching sensitive issues such as psychiatric symptoms. Although research has suggested that inquiring about psychiatric symptoms in research...
10.
Herzberg S, Hansen M, Schoonover A, Skarica B, McNulty J, Harrod T, et al.
BMJ Open
. 2019 Nov;
9(10):e025314.
PMID: 31676639
Objectives: The goal of this study was to examine the relationship between measured teamwork and adverse safety events in the prehospital emergency care of children using high-fidelity simulation. We posit...