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James Matt

Explore the profile of James Matt including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Chappell M, Li R, Smith S, Dressman B, Tromiczak E, Tripp A, et al.
J Med Chem . 2016 Dec; 59(24):10974-10993. PMID: 28002967
As part of our ongoing efforts to identify novel ligands for the metabotropic glutamate 2 and 3 (mGlu) receptors, we have incorporated substitution at the C3 and C4 positions of...
2.
Dressman B, Tromiczak E, Chappell M, Tripp A, Quimby S, Vetman T, et al.
Bioorg Med Chem Lett . 2016 Nov; 26(23):5663-5668. PMID: 27836401
Negative modulators of metabotropic glutamate 2 & 3 receptors demonstrate antidepressant-like activity in animal models and hold promise as novel therapeutic agents for the treatment of major depressive disorder. Herein...