Allie E Tripp
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Explore the profile of Allie E Tripp including associated specialties, affiliations and a list of published articles.
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4
Citations
13
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Recent Articles
1.
Chappell M, Li R, Smith S, Dressman B, Tromiczak E, Tripp A, et al.
J Med Chem
. 2016 Dec;
59(24):10974-10993.
PMID: 28002967
As part of our ongoing efforts to identify novel ligands for the metabotropic glutamate 2 and 3 (mGlu) receptors, we have incorporated substitution at the C3 and C4 positions of...
2.
Dressman B, Tromiczak E, Chappell M, Tripp A, Quimby S, Vetman T, et al.
Bioorg Med Chem Lett
. 2016 Nov;
26(23):5663-5668.
PMID: 27836401
Negative modulators of metabotropic glutamate 2 & 3 receptors demonstrate antidepressant-like activity in animal models and hold promise as novel therapeutic agents for the treatment of major depressive disorder. Herein...
3.
Wang M, Winneroski L, Ardecky R, Babine R, Brooks D, Etgen G, et al.
Bioorg Med Chem Lett
. 2004 Nov;
14(24):6113-6.
PMID: 15546740
To understand the species selectivity in a series of alpha-methyl-alpha-phenoxy carboxylic acid PPARalpha/gamma dual agonists (1-11), structure-based molecular modeling was carried out in the ligand binding pockets of both human...
4.
Xu Y, Rito C, Etgen G, Ardecky R, Bean J, Bensch W, et al.
J Med Chem
. 2004 Apr;
47(10):2422-5.
PMID: 15115385
The design and synthesis of the dual peroxisome proliferator activated receptor (PPAR) alpha/gamma agonist (S)-2-methyl-3-[4-[2-(5-methyl-2-thiophen-2-yl-oxazol-4-yl)ethoxy]phenyl]-2-phenoxypropionic acid (2) for the treatment of type 2 diabetes and associated dyslipidemia are described. 2...