James L Keck
Overview
Explore the profile of James L Keck including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
101
Citations
2848
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Cherry M, Dubiel K, Henry C, Wood E, Revitt-Mills S, Keck J, et al.
bioRxiv
. 2023 May;
PMID: 37214928
Single-stranded DNA gaps form within the chromosome during replication, repair and recombination. However, information about the extent of ssDNA creation in the genome is limited. To complement a recent whole-genome...
12.
Cox M, Goodman M, Keck J, van Oijen A, Lovett S, Robinson A
Microbiol Mol Biol Rev
. 2023 May;
87(2):e0007822.
PMID: 37212693
When replication forks encounter template lesions, one result is lesion skipping, where the stalled DNA polymerase transiently stalls, disengages, and then reinitiates downstream to leave the lesion behind in a...
13.
Duckworth A, Ducos P, McMillan S, Satyshur K, Blumenthal K, Deorio H, et al.
Nat Commun
. 2023 May;
14(1):2725.
PMID: 37169801
Bacterial replisomes often dissociate from replication forks before chromosomal replication is complete. To avoid the lethal consequences of such situations, bacteria have evolved replication restart pathways that reload replisomes onto...
14.
Osorio Garcia M, Wood E, Keck J, Cox M
J Biol Chem
. 2023 May;
299(6):104773.
PMID: 37142225
The bacterial RadD enzyme is important for multiple genome maintenance pathways, including RecA DNA strand exchange and RecA-independent suppression of DNA crossover template switching. However, much remains unknown about the...
15.
Cueny R, McMillan S, Keck J
Crit Rev Biochem Mol Biol
. 2023 Mar;
57(5-6):539-561.
PMID: 36999585
G-quadruplexes (G4s) are highly stable, non-canonical DNA or RNA structures that can form in guanine-rich stretches of nucleic acids. G4-forming sequences have been found in all domains of life, and...
16.
Bonde N, Henry C, Wood E, Cox M, Keck J
Nucleic Acids Res
. 2023 Mar;
51(8):3735-3753.
PMID: 36912097
In Escherichia coli, the single-stranded DNA-binding protein (SSB) acts as a genome maintenance organizational hub by interacting with multiple DNA metabolism proteins. Many SSB-interacting proteins (SIPs) form complexes with SSB...
17.
Cueny R, Varma S, Schmidt K, Keck J
bioRxiv
. 2023 Feb;
PMID: 36747637
Bloom syndrome helicase (BLM) is a RecQ-family helicase implicated in a variety of cellular processes, including DNA replication, DNA repair, and telomere maintenance. Mutations in human cause Bloom syndrome (BS),...
18.
McKenzie A, Henry C, Myers K, Place M, Keck J
G3 (Bethesda)
. 2022 Nov;
12(12).
PMID: 36326440
Collisions between DNA replication complexes (replisomes) and impediments such as damaged DNA or proteins tightly bound to the chromosome lead to premature dissociation of replisomes at least once per cell...
19.
Duckworth A, Keck J
Methods Enzymol
. 2022 Aug;
672:55-74.
PMID: 35934485
Formation of protein/nucleic acid complexes is essential for life. From DNA replication and repair to transcription and translation, myriad different proteins bind nucleic acids to execute their essential cellular functions....
20.
Osorio Garcia M, Satyshur K, Cox M, Keck J
PLoS One
. 2022 Apr;
17(4):e0266031.
PMID: 35482735
Genome maintenance is an essential process in all cells. In prokaryotes, the RadD protein is important for survival under conditions that include DNA-damaging radiation. Precisely how RadD participates in genome...