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James Jafali

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Articles 22
Citations 293
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Recent Articles
1.
Kwaitana D, Jafali J, Bates M, van Breevoort D, Mildestvedt T, Meland E, et al.
J Multimorb Comorb . 2025 Jan; 15:26335565251317380. PMID: 39877898
Background: Multimorbidity is a growing global concern, affecting patient outcomes and healthcare costs. In low- and middle-income countries, data on multimorbidity in primary care beyond prevalence is limited. Our study...
2.
Riches J, Jafali J, Twabi H, Chimwaza Y, Onrust M, Bilesi R, et al.
BMJ Glob Health . 2025 Jan; 10(1. PMID: 39788754
Background: Despite strong evidence-based strategies for prevention and management, global efforts to reduce deaths from postpartum haemorrhage (PPH) have failed, and it remains the leading cause of maternal mortality. We...
3.
Riches J, Chimwaza Y, Magreta Chakhame B, Milln J, Twabi H, Bilesi R, et al.
BMJ Glob Health . 2024 Nov; 9(11). PMID: 39581635
Background: Caesarean section (CS) is the most common major surgery conducted globally, with rates rising. CS also contributes to maternal morbidity and mortality, with increased risks in low-resource settings. We...
4.
Choko A, Dovel K, Kayuni S, Conserve D, Buttterworth A, Bustinduy A, et al.
Lancet Glob Health . 2024 Sep; 12(10):e1673-e1683. PMID: 39304239
Background: Undiagnosed HIV and schistosomiasis are highly prevalent among fishermen in the African Great Lakes region. We aimed to evaluate the efficacy of lakeside interventions integrating services for HIV and...
5.
Chapuma C, Twabi H, Monk E, Jafali J, Weeks A, Beales E, et al.
BMC Infect Dis . 2024 Sep; 24(1):978. PMID: 39277737
Background: Understanding the aetiological organisms causing maternal infections is crucial to inform antibiotic treatment guidelines, but such data are scarce from Sub-Saharan Africa (SSA). We performed this systematic review and...
6.
Twabi H, Jafali J, Mndala L, Riches J, Monk E, Phiri D, et al.
PLOS Glob Public Health . 2024 Aug; 4(8):e0003565. PMID: 39197033
Climate change poses a significant threat to women's health in sub-Saharan Africa, yet the impact of climate change on maternal health is rarely reported in the region. Using an existing...
7.
Fatumo S, Sathan D, Samtal C, Isewon I, Tamuhla T, Soremekun C, et al.
Genome Med . 2023 Oct; 15(1):87. PMID: 37904243
Early identification of genetic risk factors for complex diseases can enable timely interventions and prevent serious outcomes, including mortality. While the genetics underlying many Mendelian diseases have been elucidated, it...
8.
Makinde F, Tchamga M, Jafali J, Fatumo S, Chimusa E, Mulder N, et al.
Brief Bioinform . 2021 Aug; 22(6). PMID: 34415019
Over the past few years, meta-analysis has become popular among biomedical researchers for detecting biomarkers across multiple cohort studies with increased predictive power. Combining datasets from different sources increases sample...
9.
Morton B, Barnes K, Anscombe C, Jere K, Matambo P, Mandolo J, et al.
Nat Commun . 2021 Jun; 12(1):3554. PMID: 34117221
Although the COVID-19 pandemic has left no country untouched there has been limited research to understand clinical and immunological responses in African populations. Here we characterise patients hospitalised with suspected...
10.
Dantoft W, Martinez-Vicente P, Jafali J, Perez-Martinez L, Martin K, Kotzamanis K, et al.
Front Immunol . 2017 Oct; 8:1146. PMID: 28993767
Neonates and especially premature infants are highly susceptible to infection but still can have a remarkable resilience that is poorly understood. The view that neonates have an incomplete or deficient...