James G D Prendergast
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Explore the profile of James G D Prendergast including associated specialties, affiliations and a list of published articles.
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35
Citations
2770
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Recent Articles
1.
Tijjani A, Kambal S, Terefe E, Njeru R, Ogugo M, Ndambuki G, et al.
Sci Data
. 2024 Jul;
11(1):801.
PMID: 39030190
The diversity in genome resources is fundamental to designing genomic strategies for local breed improvement and utilisation. These resources also support gene discovery and enhance our understanding of the mechanisms...
2.
Talenti A, Wilkinson T, Cook E, Hemmink J, Paxton E, Mutinda M, et al.
Commun Biol
. 2024 Jul;
7(1):792.
PMID: 38951693
The African buffalo (Syncerus caffer) is a wild bovid with a historical distribution across much of sub-Saharan Africa. Genomic analysis can provide insights into the evolutionary history of the species,...
3.
Riggio V, Madder M, Labuschagne M, Callaby R, Zhao R, Djikeng A, et al.
Front Genet
. 2023 Aug;
14:1197160.
PMID: 37576560
The control of tick-borne haemoparasites in cattle largely relies on the use of acaricide drugs against the tick vectors, with some vaccination also being used against selected pathogens. These interventions...
4.
Powell J, Talenti A, Fisch A, Hemmink J, Paxton E, Toye P, et al.
Genome Biol
. 2023 May;
24(1):127.
PMID: 37218021
Background: Understanding the variation between well and poorly adapted cattle breeds to local environments and pathogens is essential for breeding cattle with improved climate and disease-resistant phenotypes. Although considerable progress...
5.
Chundru V, Marioni R, Prendergast J, Lin T, Beveridge A, Martin N, et al.
Hum Mol Genet
. 2023 Feb;
32(11):1912-1921.
PMID: 36790133
Testing the effect of rare variants on phenotypic variation is difficult due to the need for extremely large cohorts to identify associated variants given expected effect sizes. An alternative approach...
6.
Zhao R, Talenti A, Fang L, Liu S, Liu G, Chue Hong N, et al.
Commun Biol
. 2022 Sep;
5(1):1003.
PMID: 36131008
Despite the clear potential of livestock models of human functional variants to provide important insights into the biological mechanisms driving human diseases and traits, their use to date has been...
7.
Riggio V, Tijjani A, Callaby R, Talenti A, Wragg D, Obishakin E, et al.
Genet Sel Evol
. 2022 Sep;
54(1):58.
PMID: 36057548
Background: In cattle, genome-wide association studies (GWAS) have largely focused on European or Asian breeds, using genotyping arrays that were primarily designed for European cattle. Because there is growing interest...
8.
Wragg D, Cook E, de Late P, Sitt T, Hemmink J, Chepkwony M, et al.
PLoS Genet
. 2022 Apr;
18(4):e1010099.
PMID: 35446841
East Coast fever, a tick-borne cattle disease caused by the Theileria parva parasite, is among the biggest natural killers of cattle in East Africa, leading to over 1 million deaths...
9.
Zhang X, Hassan M, Prendergast J
BMC Bioinformatics
. 2022 Jan;
23(1):45.
PMID: 35042461
Background: Differential isoform usage is an important driver of inter-individual phenotypic diversity and is linked to various diseases and traits. However, accurately detecting the differential usage of different gene transcripts...
10.
de Late P, Cook E, Wragg D, Poole E, Ndambuki G, Miyunga A, et al.
Front Cell Infect Microbiol
. 2021 Nov;
11:751671.
PMID: 34804994
is the causative agent of East Coast fever and Corridor disease, which are fatal, economically important diseases of cattle in eastern, central and southern Africa. Improved methods of control of...