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James C Y Dunn

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Articles 153
Citations 2280
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Recent Articles
31.
Dubrovsky G, Ha D, Thomas A, Zhu M, Hubacher J, Itoh T, et al.
Med Acupunct . 2020 Feb; 32(1):16-23. PMID: 32104523
Neuropathic intestinal disorders continue to pose a significant burden, and current treatment options do not target the underlying cellular deficiencies. The goal of this study is to determine whether acupuncture...
32.
Koulakis J, Rouch J, Huynh N, Wu H, Dunn J, Putterman S
Pharm Res . 2020 Feb; 37(3):51. PMID: 32043171
Purpose: Bolus injection of fluid into subcutaneous tissue results in accumulation of fluid at the injection site. The fluid does not form a pool. Rather, the injection pressure forces the...
33.
Huang M, Zeki J, Sumarsono N, Coles G, Taylor J, Danzer E, et al.
Cancer Res . 2020 Jan; 80(5):1024-1035. PMID: 31900258
Neuroblastoma is a deadly pediatric solid tumor with infrequent recurrent somatic mutations. Particularly, the pathophysiology of tumors without MYCN amplification remains poorly defined. Utilizing an unbiased approach, we performed gene...
34.
Taylor J, de Ruijter V, Brewster R, Navalgund A, Axelrod L, Axelrod S, et al.
Pediatr Gastroenterol Hepatol Nutr . 2019 Nov; 22(6):518-526. PMID: 31777717
Purpose: Limited means exist to assess gastrointestinal activity in pediatric patients postoperatively. Recently, myoelectric gastrointestinal activity recorded by cutaneous patches has been shown in adult patients to be predictive of...
35.
Thomas A, Taylor J, Huynh N, Dubrovsky G, Chadarevian J, Chen A, et al.
J Pediatr Surg . 2019 Nov; 55(1):194-200. PMID: 31704043
Background: Hirschprung's disease is characterized by aganglionic bowel and often requires surgical resection. Cell-based therapies have been investigated as potential alternatives to restore functioning neurons. Skin-derived precursor cells (SKPs) differentiate...
36.
Dubrovsky G, Taylor J, Thomas A, Shekherdimian S, Dunn J
J Pediatr Surg . 2019 Nov; 55(1):158-163. PMID: 31676077
Background: Spring-mediated intestinal lengthening has been studied in numerous animal models to effectively achieve up to a 3-fold increase in length. In this study we are interested in optimizing this...
37.
Hosseini H, Wood L, Taylor J, Dubrovsky G, Portelli K, Thomas A, et al.
J Mech Behav Biomed Mater . 2019 Sep; 101:103425. PMID: 31541857
Distraction enterogenesis has been extensively studied as a potential treatment for short bowel syndrome, which is the most common subset of intestinal failure. Spring distraction uses an intraluminal axial mechanical...
38.
Hosseini H, Taylor J, Wood L, Dunn J
J Mech Behav Biomed Mater . 2019 Sep; 101:103413. PMID: 31518947
During recent years, distraction enterogenesis has been extensively studied as a treatment for short bowel syndrome, which is the most common cause of intestinal failure. Although different strategies such as...
39.
Wang P, Dubrovsky G, Dunn J, Lo Y, Liu W
Micromachines (Basel) . 2019 Aug; 10(8). PMID: 31395845
Gastrointestinal (GI) electrical stimulation has been shown in several studies to be a potential treatment option for GI motility disorders. Despite the promising preliminary research progress, however, its clinical applicability...
40.
Solorzano-Vargas R, Bjerknes M, Wu S, Wang J, Stelzner M, Dunn J, et al.
J Biol Chem . 2019 Jul; 294(41):15182-15192. PMID: 31341016
Neurogenin-3 (NEUROG3) is a helix-loop-helix (HLH) transcription factor involved in the production of endocrine cells in the intestine and pancreas of humans and mice. However, the human NEUROG3 loss-of-function phenotype...