James C Lang
Overview
Explore the profile of James C Lang including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
549
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Zhang M, Piao L, Datta J, Lang J, Xie X, Teknos T, et al.
Mol Cancer Ther
. 2015 Aug;
14(10):2313-20.
PMID: 26227488
Epithelial-restricted with serine box (ESX), a member of the ETS transcription factor family, is elevated and regulates EGFR in head and neck squamous cell carcinoma (HNSCC). However, the molecular mechanisms...
2.
Kumar B, Yadav A, Lang J, Teknos T, Kumar P
Genes Cancer
. 2015 May;
6(3-4):169-81.
PMID: 26000099
Acquisition of chemoresistance and metastatic phenotype are the major causes of treatment failure and mortality in head and neck squamous cell carcinoma (HNSCC) patients. Histone deacetylases (HDACs) have been shown...
3.
Islam M, Datta J, Lang J, Teknos T
Oral Oncol
. 2014 Feb;
50(5):448-56.
PMID: 24565984
Objective: RhoC a pro-metastatic oncogene is constitutively active in many head and neck squamous cell carcinomas. MicroRNA-138 which possesses a documented tumor suppressor function can bind to the 3'UTR of...
4.
Zhang M, Taylor C, Piao L, Datta J, Bruno P, Bhave S, et al.
Mol Cancer Ther
. 2013 Jun;
12(8):1515-25.
PMID: 23723125
EGF receptor (EGFR) is elevated in more than 90% of head and neck squamous cell carcinoma (HNSCC). However, a majority of patients with HNSCC do not respond to anti-EGFR therapeutics....
5.
Balasubramanian P, Lang J, Jatana K, Miller B, Ozer E, Old M, et al.
PLoS One
. 2012 Jul;
7(7):e42048.
PMID: 22844540
Epithelial to mesenchymal transition (EMT) has been hypothesized as a mechanism by which cells change phenotype during carcinogenesis, as well as tumor metastasis. Whether EMT is involved in cancer metastasis...
6.
Kumar B, Yadav A, Lang J, Cipolla M, Schmitt A, Arradaza N, et al.
Mol Cancer Ther
. 2012 Jun;
11(9):1988-98.
PMID: 22723337
Cisplatin is one of the commonly used chemotherapeutic drugs for the treatment of head and neck squamous cell carcinoma (HNSCC). However, acquisition of cisplatin resistance is common in patients with...
7.
Balasubramanian P, Yang L, Lang J, Jatana K, Schuller D, Agrawal A, et al.
Mol Pharm
. 2009 May;
6(5):1402-8.
PMID: 19445481
A completely negative enrichment technology was used to detect circulating tumor cells, CTCs, in the peripheral blood of head and neck cancer patients. Of 32 blood samples, 63% contained CTCs...
8.
Richards K, Zhang B, Baggerly K, Colella S, Lang J, Schuller D, et al.
PLoS One
. 2009 Mar;
4(3):e4941.
PMID: 19293934
Loss of genome-wide methylation is a common feature of cancer, and the degree of hypomethylation has been correlated with genomic instability. Global methylation of repetitive elements possibly arose as a...
9.
Yang L, Lang J, Balasubramanian P, Jatana K, Schuller D, Agrawal A, et al.
Biotechnol Bioeng
. 2008 Aug;
102(2):521-34.
PMID: 18726961
The optimization of a purely negative depletion, enrichment process for circulating tumor cells (CTCs) in the peripheral blood of head and neck cancer patients is presented. The enrichment process uses...
10.
Colella S, Richards K, Bachinski L, Baggerly K, Tsavachidis S, Lang J, et al.
Head Neck
. 2008 Jul;
30(10):1273-83.
PMID: 18642293
Background: Metastases are the primary cause of cancer treatment failure and death, yet metastatic mechanisms remain incompletely understood. Methods: We studied the molecular basis of head and neck cancer metastasis...