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James B Brown

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Articles 63
Citations 10558
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Recent Articles
1.
He Y, Bond-Lamberty B, Myers-Pigg A, Newcomer M, Ladau J, Holmquist J, et al.
Heliyon . 2024 May; 10(9):e30470. PMID: 38726202
Coastal terrestrial-aquatic interfaces (TAIs) are crucial contributors to global biogeochemical cycles and carbon exchange. The soil carbon dioxide (CO) efflux in these transition zones is however poorly understood due to...
2.
Ladau J, Brodie E, Falco N, Bansal I, Hoffman E, Joachimiak M, et al.
Infect Dis Model . 2024 Apr; 9(2):634-643. PMID: 38572058
Objectives: We aim to estimate geographic variability in total numbers of infections and infection fatality ratios (IFR; the number of deaths caused by an infection per 1,000 infected people) when...
3.
Inman J, Wu Y, Chen L, Brydon E, Ghosh D, Wan K, et al.
Sci Rep . 2024 Mar; 14(1):6119. PMID: 38480827
Non-invasive methods of detecting radiation exposure show promise to improve upon current approaches to biological dosimetry in ease, speed, and accuracy. Here we developed a pipeline that employs Fourier transform...
4.
Bosch J, Keith N, Escobedo F, Fisher W, LaGraff J, Rabasco J, et al.
Cell Rep . 2024 Jan; 43(2):113737. PMID: 38265936
No abstract available.
5.
Wang Q, Tang T, Youlton N, Weldy C, Kenney A, Ronen O, et al.
Res Sq . 2023 Dec; PMID: 38045390
The combinatorial effect of genetic variants is often assumed to be additive. Although genetic variation can clearly interact non-additively, methods to uncover epistatic relationships remain in their infancy. We develop...
6.
Wang Q, Tang T, Youlton N, Weldy C, Kenney A, Ronen O, et al.
medRxiv . 2023 Nov; PMID: 37987017
The combinatorial effect of genetic variants is often assumed to be additive. Although genetic variation can clearly interact non-additively, methods to uncover epistatic relationships remain in their infancy. We develop...
7.
Bosch J, Keith N, Escobedo F, Fisher W, LaGraff J, Rabasco J, et al.
Cell Rep . 2023 Oct; 42(11):113311. PMID: 37889754
Short polypeptides encoded by small open reading frames (smORFs) are ubiquitously found in eukaryotic genomes and are important regulators of physiology, development, and mitochondrial processes. Here, we focus on a...
8.
Brown J, Langley S, Snijders A, Wan K, Morris S, Booth B, et al.
Commun Biol . 2021 Nov; 4(1):1324. PMID: 34819611
The gut microbiome produces vitamins, nutrients, and neurotransmitters, and helps to modulate the host immune system-and also plays a major role in the metabolism of many exogenous compounds, including drugs...
9.
Eastwood N, Stubbings W, Abou-Elwafa Abdallah M, Durance I, Paavola J, Dallimer M, et al.
Trends Ecol Evol . 2021 Nov; 37(2):138-146. PMID: 34772522
Transdisciplinary solutions are needed to achieve the sustainability of ecosystem services for future generations. We propose a framework to identify the causes of ecosystem function loss and to forecast the...
10.
Joshi R, Gebauer N, Bontha M, Khazaieli M, James R, Brown J, et al.
J Phys Chem B . 2021 Oct; 125(44):12166-12176. PMID: 34662142
The prerequisite of therapeutic drug design and discovery is to identify novel molecules and developing lead candidates with desired biophysical and biochemical properties. Deep generative models have demonstrated their ability...