James A L Fenton
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Explore the profile of James A L Fenton including associated specialties, affiliations and a list of published articles.
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17
Citations
523
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Recent Articles
1.
Pratt G, Fenton J, Allsup D, Fegan C, Morgan G, Jackson G, et al.
Br J Haematol
. 2010 Apr;
150(3):371-3.
PMID: 20408839
No abstract available.
2.
Rawstron A, Bennett F, OConnor S, Kwok M, Fenton J, Plummer M, et al.
N Engl J Med
. 2008 Aug;
359(6):575-83.
PMID: 18687638
Background: A diagnosis of chronic lymphocytic leukemia (CLL) requires a count of over 5000 circulating CLL-phenotype cells per cubic millimeter. Asymptomatic persons with fewer CLL-phenotype cells have monoclonal B-cell lymphocytosis...
3.
Barrans S, Fenton J, Ventura R, Smith A, Banham A, Jack A
Haematologica
. 2007 Jun;
92(6):863-4.
PMID: 17550867
Strong uniform expression of FOXP1 protein occurs in a subgroup of non-germinal centre (GC) diffuse large B-cell lymphomas (DLBCL). We have investigated gene rearrangement as a potential mechanism for deregulated...
4.
Rollett R, Wilkinson E, Gonzalez D, Fenton J, Short M, Evans P, et al.
Clin Lymphoma Myeloma
. 2006 Aug;
7(1):70-2.
PMID: 16879773
In this study, we used IGH sequence analysis to assess the maturational status of Waldenstrom's (WM) macroglobulinemia and its putative precursor immunoglobulin (Ig)-M monoclonal gammopathy of undetermined significance (MGUS). IGH...
5.
Fenton J, Schuuring E, Barrans S, Banham A, Rollinson S, Morgan G, et al.
Genes Chromosomes Cancer
. 2005 Oct;
45(2):164-8.
PMID: 16252263
Strong expression of Forkhead box-P1 (FOXP1), a winged-helix transcription factor, has been identified as an independent prognostic factor in diffuse large B-cell lymphoma (DLBCL). However, possible mechanisms of deregulation of...
6.
Guikema J, Fenton J, de Boer C, Kleiverda K, Brink A, Raap A, et al.
Genes Chromosomes Cancer
. 2004 Nov;
42(2):164-9.
PMID: 15543623
Chromosomal translocations involving the immunoglobulin (Ig) receptor loci usually disrupt and silence these loci. On the basis of observations in follicular lymphoma (FL) with downstream Ig heavy chain (IGH) class...
7.
Ferber M, Eilers P, Schuuring E, Fenton J, Fleuren G, Kenter G, et al.
Cancer Genet Cytogenet
. 2004 Sep;
154(1):1-9.
PMID: 15381365
Molecular cytogenetic analysis frequently shows human papillomavirus (HPV) integration near translocation breakpoints in cervical cancer cells. We have recently described a cluster of HPV18 integrations in the distal end of...
8.
Dring A, Davies F, Fenton J, Roddam P, Scott K, Gonzalez D, et al.
Clin Cancer Res
. 2004 Sep;
10(17):5692-701.
PMID: 15355895
Purpose: Our purpose in this report was to define genes and pathways dysregulated as a consequence of the t(4;14) in myeloma, and to gain insight into the downstream functional effects...
9.
Barrans S, Fenton J, Banham A, Owen R, Jack A
Blood
. 2004 Jul;
104(9):2933-5.
PMID: 15238418
FOXP1 (Forkhead box-P1) is a winged-helix transcription factor that is differentially expressed in resting and activated B cells. FOXP1 expression has been demonstrated in a subset of diffuse large B-cell...
10.
Fenton J, Pratt G, Rothwell D, Rawstron A, Morgan G
Genes Chromosomes Cancer
. 2003 Dec;
39(2):151-5.
PMID: 14695995
We describe the characterization of the genomic DNA breakpoints of two multiple myeloma (MM) patients with t(11;14). IGH translocation events are present in many MM tumors, and it is proposed...