Jaladanki N Rao
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Explore the profile of Jaladanki N Rao including associated specialties, affiliations and a list of published articles.
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102
Citations
2676
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Recent Articles
1.
Chung H, Xiao L, Han N, Chen J, Yao V, Cairns C, et al.
JCI Insight
. 2024 Jan;
9(4).
PMID: 38227372
Circular RNAs (circRNAs) are highly expressed in the mammalian intestinal epithelium, but their functions remain largely unknown. Here, we identified the circRNA Cdr1as as a repressor of intestinal epithelial regeneration...
2.
Xiao L, Warner B, Mallard C, Chung H, Shetty A, Brantner C, et al.
Life Sci Alliance
. 2023 Sep;
6(11).
PMID: 37696579
Rapid self-renewal of the intestinal epithelium requires the activity of intestinal stem cells (ISCs) that are intermingled with Paneth cells (PCs) at the crypt base. PCs provide multiple secreted and...
3.
Li R, Rao J, Smith A, Chung H, Xiao L, Wang J, et al.
Am J Physiol Cell Physiol
. 2023 Jan;
324(2):C565-C572.
PMID: 36622069
Intestinal epithelial barrier defects occur commonly during a variety of pathological conditions, though their underlying mechanisms are not completely understood. Sphingosine-1-phosphate (S1P) has been shown to be a critical regulator...
4.
Ma X, Xiao L, Wen S, Yu T, Sharma S, Chung H, et al.
EMBO Rep
. 2022 Nov;
24(2):e54925.
PMID: 36440604
Vault RNAs (vtRNAs) are small noncoding RNAs and highly expressed in many eukaryotes. Here, we identified vtRNA2-1 as a novel regulator of the intestinal barrier via interaction with RNA-binding protein...
5.
Yu T, Kalakonda S, Liu X, Han N, Chung H, Xiao L, et al.
JCI Insight
. 2022 Oct;
7(19).
PMID: 36214222
Intestinal epithelial integrity is commonly disrupted in patients with critical disorders, but the exact underlying mechanisms are unclear. Long noncoding RNAs transcribed from ultraconserved regions (T-UCRs) control different cell functions...
6.
Wang S, Rathor N, Kwon M, Xiao L, Chung H, Turner D, et al.
Am J Physiol Cell Physiol
. 2022 Mar;
322(4):C712-C722.
PMID: 35235424
Early gut epithelial restitution reseals superficial wounds after acute injury, but the exact mechanism underlying this rapid mucosal repair remains largely unknown. MicroRNA-195 (miR-195) is highly expressed in the gut...
7.
Si R, Cabrera J, Tsuji-Hosokawa A, Guo R, Watanabe M, Gao L, et al.
JCI Insight
. 2021 Nov;
6(21).
PMID: 34747371
Patients with diabetes with coronary microvascular disease (CMD) exhibit higher cardiac mortality than patients without CMD. However, the molecular mechanism by which diabetes promotes CMD is poorly understood. RNA-binding protein...
8.
Xiao L, Ma X, Luo J, Chung H, Kwon M, Yu T, et al.
Gastroenterology
. 2021 Jun;
161(4):1303-1317.e3.
PMID: 34116030
Background & Aims: Circular RNAs (circRNAs) are a class of endogenous noncoding RNAs that form covalently closed circles. Although circRNAs influence many biological processes, little is known about their role...
9.
Rathor N, Chung H, Song J, Wang S, Wang J, Rao J
Physiol Rep
. 2021 May;
9(9):e14864.
PMID: 33991460
Gut epithelial restitution after superficial wounding is an important repair modality regulated by numerous factors including Ca signaling and cellular polyamines. Transient receptor potential canonical-1 (TRPC1) functions as a store-operated...
10.
Kwon M, Chung H, Xiao L, Yu T, Wang S, Piao J, et al.
Am J Physiol Cell Physiol
. 2021 Mar;
320(6):C1042-C1054.
PMID: 33788631
Intestinal Tuft cells sense luminal contents to influence the mucosal immune response against eukaryotic infection. Paneth cells secrete antimicrobial proteins as part of the mucosal protective barrier. Defects in Tuft...