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Jakub Zahumensky

Explore the profile of Jakub Zahumensky including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Naseem S, Zahumensky J, Lanze C, Douglas L, Malinsky J, Konopka J
mSphere . 2024 Nov; 9(12):e0039124. PMID: 39611854
Importance: The ability of to grow invasively in the host and resist stress is critical for it to be an effective human pathogen. Identifying the genes that promote these processes...
2.
Zahumensky J, Malinsky J
Biol Methods Protoc . 2024 Nov; 9(1):bpae075. PMID: 39484095
Fluorescence microscopy images of biological samples contain valuable information but require rigorous analysis for accurate and reliable determination of changes in protein localization, fluorescence intensity, and morphology of the studied...
3.
Mondal S, Zahumensky J, Vesela P, Malinsky J
Heliyon . 2024 Oct; 10(19):e38786. PMID: 39416838
The regulation of gene expression in eukaryotes relies largely on the action of exoribonucleases, evolutionarily conserved enzymes that digest decapped messenger RNAs in the 5'-3' direction. The activity of Xrn1,...
4.
Filipi T, Matusova Z, Abaffy P, Vanatko O, Tureckova J, Benesova S, et al.
Sci Rep . 2023 Apr; 13(1):6538. PMID: 37085528
The role of glia in amyotrophic lateral sclerosis (ALS) is undeniable. Their disease-related activity has been extensively studied in the spinal cord, but only partly in the brain. We present...
5.
Vesela P, Zahumensky J, Malinsky J
J Cell Sci . 2023 Jan; 136(3). PMID: 36601791
Eisosomes are large hemitubular structures that underlie the invaginated microdomains in the plasma membrane of various ascomycetous fungi, lichens and unicellular algae. In fungi, they are organized by BAR-domain containing...
6.
Balazova M, Vesela P, Babelova L, Durisova I, Kanovicova P, Zahumensky J, et al.
Microbiol Spectr . 2022 Nov; 10(6):e0248922. PMID: 36377885
The absence of Isc1, the yeast homologue of mammalian neutral sphingomyelinase type 2, leads to severe mitochondrial dysfunction. We show that the deletion of another type C phospholipase, the phosphatidylglycerol...
7.
Zahumensky J, Mota Fernandes C, Vesela P, Del Poeta M, Konopka J, Malinsky J
Microbiol Spectr . 2022 Jun; 10(4):e0196122. PMID: 35758748
Sphingolipids are essential building blocks of eukaryotic membranes and important signaling molecules that are regulated tightly in response to environmental and physiological inputs. While their biosynthetic pathway has been well-described,...
8.
Kanovicova P, Cermakova P, Kubalova D, Babelova L, Vesela P, Valachovic M, et al.
J Biol Chem . 2021 Dec; 298(1):101462. PMID: 34864056
Barth syndrome (BTHS) is an inherited mitochondrial disorder characterized by a decrease in total cardiolipin and the accumulation of its precursor monolysocardiolipin due to the loss of the transacylase enzyme...
9.
Vaskovicova K, Vesela P, Zahumensky J, Folkova D, Balazova M, Malinsky J
Biomolecules . 2020 Oct; 10(11). PMID: 33114062
Membrane proteins are targeted not only to specific membranes in the cell architecture, but also to distinct lateral microdomains within individual membranes to properly execute their biological functions. Yeast tetraspan...
10.
Chen Y, Zhao G, Zahumensky J, Honey S, Futcher B
Mol Cell . 2020 Apr; 78(2):359-370.e6. PMID: 32246903
Yeast cells must grow to a critical size before committing to division. It is unknown how size is measured. We find that as cells grow, mRNAs for some cell-cycle activators...