James B Konopka
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Explore the profile of James B Konopka including associated specialties, affiliations and a list of published articles.
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Articles
78
Citations
2016
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Recent Articles
1.
Naseem S, Zahumensky J, Lanze C, Douglas L, Malinsky J, Konopka J
mSphere
. 2024 Nov;
9(12):e0039124.
PMID: 39611854
Importance: The ability of to grow invasively in the host and resist stress is critical for it to be an effective human pathogen. Identifying the genes that promote these processes...
2.
Swenson K, Min K, Konopka J
PLoS Genet
. 2024 Oct;
20(10):e1011455.
PMID: 39432552
Human fungal pathogens must survive diverse reactive oxygen species (ROS) produced by host immune cells that can oxidize a range of cellular molecules including proteins, lipids, and DNA. Formation of...
3.
Lanze C, Konopka J
Mol Biol Cell
. 2024 May;
35(7):ar99.
PMID: 38776129
The human fungal pathogen can cause lethal systemic infections due to its ability to resist stress from the host and to undergo invasive hyphal growth. Previous studies showed that plasma...
4.
Douglas L, Min K, Konopka J
mBio
. 2023 Nov;
14(6):e0267123.
PMID: 38032204
Hypochlorous acid (HOCl), commonly known as bleach, is generated during the respiratory burst by phagocytes and is a key weapon used to attack and other microbial pathogens. However, the effects...
5.
Gandra R, Johnson C, Nett J, Konopka J
mSphere
. 2023 Nov;
8(6):e0050723.
PMID: 38032185
is an important human pathogen that can cause lethal systemic infections. The ability of to colonize and establish infections is closely tied to its highly adaptable nature and capacity to...
6.
Gandra R, Johnson C, Nett J, Konopka J
bioRxiv
. 2023 Sep;
PMID: 37732195
The fungal pathogen is capable of causing lethal infections in humans. Its pathogenic potential is due in part to the ability to resist various stress conditions in the host, including...
7.
Zahumensky J, Mota Fernandes C, Vesela P, Del Poeta M, Konopka J, Malinsky J
Microbiol Spectr
. 2022 Jun;
10(4):e0196122.
PMID: 35758748
Sphingolipids are essential building blocks of eukaryotic membranes and important signaling molecules that are regulated tightly in response to environmental and physiological inputs. While their biosynthetic pathway has been well-described,...
8.
Dumont M, Konopka J
Biomolecules
. 2022 Jun;
12(6).
PMID: 35740886
The α-factor mating pheromone receptor (Ste2p) has been studied as a model for the large medically important family of G protein-coupled receptors. Diverse yeast genetic screens and high-throughput mutagenesis of...
9.
Konopka J
mBio
. 2022 Apr;
13(3):e0036622.
PMID: 35467420
Phosphatidylinositol lipids regulate key processes, including vesicle trafficking and cell polarity. A recent study identified novel roles for phosphatidylinositol 4-phosphate (PIP) in the plasma membrane of the fungal pathogen Candida...
10.
Lanze C, Zhou S, Konopka J
Mol Microbiol
. 2021 Aug;
116(4):1201-1215.
PMID: 34465004
MCC/eisosome subdomains of the plasma membrane promote proper cell wall morphogenesis that is critical for the fungal pathogen Candida albicans to grow invasively and resist stressful environments in the host....