Jakob McBroome
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Explore the profile of Jakob McBroome including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
243
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0
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Recent Articles
1.
Goya S, Ruis C, Neher R, Meijer A, Aziz A, Hinrichs A, et al.
Emerg Infect Dis
. 2024 Jul;
30(8):1631-1641.
PMID: 39043393
A globally implemented unified phylogenetic classification for human respiratory syncytial virus (HRSV) below the subgroup level remains elusive. We formulated global consensus of HRSV classification on the basis of the...
2.
McBroome J, de Bernardi Schneider A, Roemer C, Wolfinger M, Hinrichs A, OToole A, et al.
Nat Microbiol
. 2024 Feb;
9(2):550-560.
PMID: 38316930
Pathogen lineage nomenclature systems are a key component of effective communication and collaboration for researchers and public health workers. Since February 2021, the Pango dynamic lineage nomenclature for SARS-CoV-2 has...
3.
Kramer A, Thornlow B, Ye C, De Maio N, McBroome J, Hinrichs A, et al.
Syst Biol
. 2023 May;
72(5):1039-1051.
PMID: 37232476
Phylogenetics has been foundational to SARS-CoV-2 research and public health policy, assisting in genomic surveillance, contact tracing, and assessing emergence and spread of new variants. However, phylogenetic analyses of SARS-CoV-2...
4.
Ruis C, Peacock T, Polo L, Masone D, Alvarez M, Hinrichs A, et al.
Microb Genom
. 2023 May;
9(5).
PMID: 37185044
Exposure to different mutagens leaves distinct mutational patterns that can allow inference of pathogen replication niches. We therefore investigated whether SARS-CoV-2 mutational spectra might show lineage-specific differences, dependent on the...
5.
Turakhia Y, Thornlow B, Hinrichs A, McBroome J, Ayala N, Ye C, et al.
Nature
. 2022 Aug;
609(7929):994-997.
PMID: 35952714
Accurate and timely detection of recombinant lineages is crucial for interpreting genetic variation, reconstructing epidemic spread, identifying selection and variants of interest, and accurately performing phylogenetic analyses. During the SARS-CoV-2...
6.
McBroome J, Martin J, de Bernardi Schneider A, Turakhia Y, Corbett-Detig R
Virus Evol
. 2022 Jun;
8(1):veac048.
PMID: 35769891
The unprecedented severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) global sequencing effort has suffered from an analytical bottleneck. Many existing methods for phylogenetic analysis are designed for sparse, static datasets...
7.
Thornlow B, Kramer A, Ye C, De Maio N, McBroome J, Hinrichs A, et al.
bioRxiv
. 2022 May;
PMID: 35611334
Phylogenetics has been foundational to SARS-CoV-2 research and public health policy, assisting in genomic surveillance, contact tracing, and assessing emergence and spread of new variants. However, phylogenetic analyses of SARS-CoV-2...
8.
Ye C, Thornlow B, Kramer A, McBroome J, Hinrichs A, Corbett-Detig R, et al.
bioRxiv
. 2021 Dec;
PMID: 34927180
Phylogenetics has been central to the genomic surveillance, epidemiology and contact tracing efforts during the COVD-19 pandemic. But the massive scale of genomic sequencing has rendered the pre-pandemic tools inadequate...
9.
McBroome J, Thornlow B, Hinrichs A, Kramer A, De Maio N, Goldman N, et al.
Mol Biol Evol
. 2021 Sep;
38(12):5819-5824.
PMID: 34469548
The vast scale of SARS-CoV-2 sequencing data has made it increasingly challenging to comprehensively analyze all available data using existing tools and file formats. To address this, we present a...
10.
Thornlow B, Hinrichs A, Jain M, Dhillon N, La S, Kapp J, et al.
bioRxiv
. 2021 Apr;
PMID: 33851162
We report a SARS-CoV-2 lineage that shares N501Y, P681H, and other mutations with known variants of concern, such as B.1.1.7. This lineage, which we refer to as B.1.x (COG-UK sometimes...