Robert Lanfear
Overview
Explore the profile of Robert Lanfear including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
83
Citations
11330
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ren H, Wong T, Minh B, Lanfear R
Mol Biol Evol
. 2024 Dec;
42(1).
PMID: 39715360
In phylogenetic studies, both partitioned models and mixture models are used to account for heterogeneity in molecular evolution among the sites of DNA sequence alignments. Partitioned models require the user...
2.
Lanfear R, Hahn M
Mol Biol Evol
. 2024 Oct;
41(11).
PMID: 39418118
As phylogenomic datasets have grown in size, researchers have developed new ways to measure biological variation and to assess statistical support for specific branches. Larger datasets have more sites and...
3.
Banos H, Wong T, Daneau J, Susko E, Minh B, Lanfear R, et al.
Mol Biol Evol
. 2024 Aug;
41(9).
PMID: 39158305
Profile mixture models capture distinct biochemical constraints on the amino acid substitution process at different sites in proteins. These models feature a mixture of time-reversible models with a common matrix...
4.
Wong T, Cherryh C, Rodrigo A, Hahn M, Minh B, Lanfear R
Syst Biol
. 2024 Feb;
73(2):375-391.
PMID: 38421146
Hundreds or thousands of loci are now routinely used in modern phylogenomic studies. Concatenation approaches to tree inference assume that there is a single topology for the entire dataset, but...
5.
Wang W, Barbetti J, Wong T, Thornlow B, Corbett-Detig R, Turakhia Y, et al.
Bioinformatics
. 2023 Aug;
39(9).
PMID: 37651445
Motivation: Neighbour-Joining is one of the most widely used distance-based phylogenetic inference methods. However, current implementations do not scale well for datasets with more than 10 000 sequences. Given the...
6.
Kramer A, Thornlow B, Ye C, De Maio N, McBroome J, Hinrichs A, et al.
Syst Biol
. 2023 May;
72(5):1039-1051.
PMID: 37232476
Phylogenetics has been foundational to SARS-CoV-2 research and public health policy, assisting in genomic surveillance, contact tracing, and assessing emergence and spread of new variants. However, phylogenetic analyses of SARS-CoV-2...
7.
Moravec J, Lanfear R, Spector D, Diermeier S, Gavryushkin A
J Comput Biol
. 2022 Dec;
30(4):518-537.
PMID: 36475926
Phylogenetic methods are emerging as a useful tool to understand cancer evolutionary dynamics, including tumor structure, heterogeneity, and progression. Most currently used approaches utilize either bulk whole genome sequencing or...
8.
Mo Y, Lanfear R, Hahn M, Minh B
Bioinformatics
. 2022 Nov;
39(1).
PMID: 36383168
Motivation: Site concordance factors (sCFs) have become a widely used way to summarize discordance in phylogenomic datasets. However, the original version of sCFs was calculated by sampling a quartet of...
9.
Turakhia Y, Thornlow B, Hinrichs A, McBroome J, Ayala N, Ye C, et al.
Nature
. 2022 Aug;
609(7929):994-997.
PMID: 35952714
Accurate and timely detection of recombinant lineages is crucial for interpreting genetic variation, reconstructing epidemic spread, identifying selection and variants of interest, and accurately performing phylogenetic analyses. During the SARS-CoV-2...
10.
Ye C, Thornlow B, Hinrichs A, Kramer A, Mirchandani C, Torvi D, et al.
Bioinformatics
. 2022 Jun;
38(15):3734-3740.
PMID: 35731204
Motivation: Phylogenetic tree optimization is necessary for precise analysis of evolutionary and transmission dynamics, but existing tools are inadequate for handling the scale and pace of data produced during the...