Jake Lin
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Explore the profile of Jake Lin including associated specialties, affiliations and a list of published articles.
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30
Citations
414
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Recent Articles
11.
Ripatti P, Ramo J, Mars N, Fu Y, Lin J, Soderlund S, et al.
Circ Genom Precis Med
. 2020 Mar;
13(2):e002725.
PMID: 32154731
Background: Hyperlipidemia is a highly heritable risk factor for coronary artery disease (CAD). While monogenic familial hypercholesterolemia associates with severely increased CAD risk, it remains less clear to what extent...
12.
Lindfors K, Lin J, Lee H, Hyoty H, Nykter M, Kurppa K, et al.
Gut
. 2019 Nov;
69(8):1416-1422.
PMID: 31744911
Objective: Higher gluten intake, frequent gastrointestinal infections and adenovirus, enterovirus, rotavirus and reovirus have been proposed as environmental triggers for coeliac disease. However, it is not known whether an interaction...
13.
Mehtonen J, Polonen P, Hayrynen S, Dufva O, Lin J, Liuksiala T, et al.
Nucleic Acids Res
. 2019 Jul;
47(13):e76.
PMID: 31329928
Existing large gene expression data repositories hold enormous potential to elucidate disease mechanisms, characterize changes in cellular pathways, and to stratify patients based on molecular profiles. To achieve this goal,...
14.
Polonen P, Mehtonen J, Lin J, Liuksiala T, Hayrynen S, Teppo S, et al.
Cancer Res
. 2019 Apr;
79(10):2466-2479.
PMID: 30940663
Large collections of genome-wide data can facilitate the characterization of disease states and subtypes, permitting pan-cancer analysis of molecular phenotypes and evaluation of disease context for new therapeutic approaches. We...
15.
Lin J, Kimura B, Oikarinen S, Nykter M
Methods Mol Biol
. 2018 Aug;
1838:261-272.
PMID: 30129002
The human microbiome project via application of metagenomic next-generation sequencing techniques has found surprising large and diverse amounts of microbial sequences across different body sites. There is a wave of...
16.
Nurminen N, Lin J, Gronroos M, Puhakka R, Kramna L, Vari H, et al.
Future Microbiol
. 2018 May;
13:737-744.
PMID: 29771153
Aim: Current attempts to modulate the human microbiota and immune responses are based on probiotics or human-derived bacterial transplants. We investigated microbial modulation by soil and plant-based material. Materials &...
17.
Kramna L, Drevinek P, Lin J, Kulich M, Cinek O
Folia Microbiol (Praha)
. 2017 Nov;
63(2):237-248.
PMID: 29127619
The lung in cystic fibrosis (CF) is home to numerous pathogens that shorten the lives of patients. The aim of the present study was to assess changes in the lung...
18.
Lin J, Kramna L, Autio R, Hyoty H, Nykter M, Cinek O
BMC Genomics
. 2017 May;
18(1):378.
PMID: 28506246
Background: Next generation sequencing (NGS) technology allows laboratories to investigate virome composition in clinical and environmental samples in a culture-independent way. There is a need for bioinformatic tools capable of...
19.
Cinek O, Kramna L, Lin J, Oikarinen S, Kolarova K, Ilonen J, et al.
Pediatr Diabetes
. 2016 Nov;
18(7):588-598.
PMID: 27860030
Background: We set out to explore associations between the stool bacteriome profiles and early-onset islet autoimmunity, taking into account the interactions with the virus component of the microbiome. Methods: Serial...
20.
Galhardo M, Sinkkonen L, Berninger P, Lin J, Sauter T, Heinaniemi M
Genom Data
. 2015 Oct;
2:246-8.
PMID: 26484102
Obesity is an ever-growing epidemic where tissue homeostasis is influenced by the differentiation of adipocytes that function in lipid metabolism, endocrine and inflammatory processes. While this differentiation process has been...