Jae Hong Im
Overview
Explore the profile of Jae Hong Im including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
18
Citations
1335
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0
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Recent Articles
1.
Kim E, Im J, Han J, Cho W
Bioorg Med Chem Lett
. 2024 Jan;
99:129622.
PMID: 38244940
Alzheimer's disease (AD) remains an incurable neurodegenerative condition that poses a threat to humanity. Immune signaling in the brain, particularly the NLR family pyrin domain containing 3 (NLRP3), is currently...
2.
Li X, Han J, Bujaranipalli S, He J, Kim E, Kim H, et al.
Eur J Med Chem
. 2022 May;
238:114444.
PMID: 35588599
The neurofibrillary tangles (NFTs) formed from hyperphosphorylation of tau protein are closely associated with Alzheimer's disease (AD). O-GlcNAcylation of tau can negatively regulate hyperphosphorylation and the O-GlcNAcase (OGA) catalyzes the...
3.
Im J, Muschel R
Bio Protoc
. 2021 Aug;
7(4):e2132.
PMID: 34458453
Platelets and coagulation have long been known to be essential for metastasis in experimental models. In order to study the interactions between tumor cells, platelets and endothelium, we have adapted...
4.
Im J, Buzzelli J, Jones K, Franchini F, Gordon-Weeks A, Markelc B, et al.
Nat Commun
. 2020 Aug;
11(1):4064.
PMID: 32792542
Regulation of the programming of tumour-associated macrophages (TAMs) controls tumour growth and anti-tumour immunity. We examined the role of FGF2 in that regulation. Tumours in mice genetically deficient in low-molecular...
5.
Jones K, Tiersma J, Yuzhalin A, Gordon-Weeks A, Buzzelli J, Im J, et al.
EMBO Mol Med
. 2018 Nov;
10(12).
PMID: 30442705
Emerging evidence suggests a role for radiation in eliciting anti-tumour immunity. We aimed to investigate the role of macrophages in modulating the immune response to radiation. Irradiation to murine tumours...
6.
Reymond N, Im J, Garg R, Cox S, Soyer M, Riou P, et al.
Mol Oncol
. 2015 Feb;
9(6):1043-55.
PMID: 25677806
RhoC is a member of the Rho GTPase family that is implicated in cancer progression by stimulating cancer cell invasiveness. Here we report that RhoC regulates the interaction of cancer...
7.
Im J, Muschel R
Hepatobiliary Surg Nutr
. 2014 Feb;
1(1):55-6.
PMID: 24570903
No abstract available.
8.
Lim S, Gordon-Weeks A, Zhao L, Tapmeier T, Im J, Cao Y, et al.
Oncoimmunology
. 2013 Jun;
2(3):e23187.
PMID: 23802071
Tumor-infiltrating immune cells play important roles in metastasis. We have recently revealed the recruitment of a specific myeloid cell subset (CD11b/Gr1) to hepatic metastases. Such a recruitment relies on CCL2/CCR2...
9.
Reymond N, Im J, Garg R, Vega F, Borda DAgua B, Riou P, et al.
J Cell Biol
. 2012 Nov;
199(4):653-68.
PMID: 23148235
Cancer cells interact with endothelial cells during the process of metastatic spreading. Here, we use a small interfering RNA screen targeting Rho GTPases in cancer cells to identify Cdc42 as...
10.
Zhao L, Lim S, Gordon-Weeks A, Tapmeier T, Im J, Cao Y, et al.
Hepatology
. 2012 Oct;
57(2):829-39.
PMID: 23081697
Unlabelled: Liver metastasis from colorectal cancer is a leading cause of cancer mortality. Myeloid cells play pivotal roles in the metastatic process, but their prometastatic functions in liver metastasis remain...