Jae-Gyu Kim
Overview
Explore the profile of Jae-Gyu Kim including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
27
Citations
576
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0
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Recent Articles
1.
Hamza A, Cho J, Cap K, Hossain A, Kim J, Park J
Free Radic Biol Med
. 2023 Sep;
208:614-629.
PMID: 37722568
In the tumor microenvironment (TME), communication between cancer cells and tumor-associated macrophages (TAMs) through secreted extracellular proteins promotes cancer progression. Here, we observed that co-culturing cancer cells (4T1) and macrophage...
2.
Hossain A, Islam R, Kim J, Dogsom O, Cap K, Park J
Biomedicines
. 2022 Jun;
10(6).
PMID: 35740278
Insulin potently promotes cell proliferation and anabolic metabolism along with a reduction in blood glucose levels. Pyruvate dehydrogenase (PDH) plays a pivotal role in glucose metabolism. Insulin increase PDH activity...
3.
Min J, Park H, Lee Y, Kim J, Kim J, Park J
Biomedicines
. 2022 May;
10(5).
PMID: 35625853
Src, a non-receptor tyrosine kinase, was first discovered as a prototype oncogene and has been shown to critical for cancer progression for a variety of tissues. Src activity is regulated...
4.
Park J, Kang C, Seo H, Shin J, Kym S, Park Y, et al.
Cancers (Basel)
. 2021 Sep;
13(18).
PMID: 34572913
Early detection is crucial for improving the prognosis of gastric cancer, but there are no non-invasive markers for the early diagnosis of gastric cancer in real clinical settings. Recently, bacteria-derived...
5.
Lee Y, Min J, Kim J, Cap K, Islam R, Hossain A, et al.
J Cell Physiol
. 2021 Jul;
237(1):128-148.
PMID: 34311499
Glucose metabolism is a mechanism by which energy is produced in form of adenosine triphosphate (ATP) by mitochondria and precursor metabolites are supplied to enable the ultimate enrichment of mature...
6.
Kim J, Mahmud S, Min J, Lee Y, Kim H, Kang D, et al.
Redox Biol
. 2021 Jan;
40:101842.
PMID: 33388549
In the Wnt canonical pathway, Wnt3A has been known to stabilize β-catenin. In the non-canonical Wnt signaling pathway, Wnt is known to activate Rho GTPases. The correlation between canonical and...
7.
Cap K, Jung Y, Choi B, Hyeon S, Kim J, Min J, et al.
Redox Biol
. 2020 Feb;
32:101446.
PMID: 32046944
Both the accumulation of Amyloid-β (Aβ) in plaques and phosphorylation of Tau protein (p-Tau) in neurofibrillary tangles have been identified as two major symptomatic features of Alzheimer's disease (AD). Despite...
8.
Cap K, Kim J, Hamza A, Park J
Biochem Biophys Res Commun
. 2020 Jan;
523(4):972-978.
PMID: 31973815
Optimal levels of reactive oxygen species (ROS) play a critical role in cellular physiological function. For production of intracellular superoxide, NADPH oxidase is one of the sources. Rac1/2 and RhoA...
9.
Islam R, Kim J, Park Y, Cho J, Cap K, Kho A, et al.
FASEB J
. 2018 Sep;
33(2):2072-2083.
PMID: 30226812
Insulin is a critical signaling molecule in reducing blood glucose levels, and pyruvate dehydrogenase (PDH) is an essential enzyme in regulating glucose metabolism. However, the insulin effect on PDH function...
10.
Kim J, Islam R, Cho J, Jeong H, Cap K, Park Y, et al.
J Cell Physiol
. 2018 Jan;
233(9):6381-6392.
PMID: 29377108
RhoA GTPase plays a variety of functions in regulation of cytoskeletal proteins, cellular morphology, and migration along with various proliferation and transcriptional activity in cells. RhoA activity is regulated by...