Jae-Gyu Kim
Overview
Explore the profile of Jae-Gyu Kim including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
576
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0
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Recent Articles
11.
Choi E, Kim J, Kim H, Cho J, Jeong H, Park Y, et al.
Small GTPases
. 2017 Dec;
11(2):95-102.
PMID: 29199510
Rho GTPases play significant roles in cellular function and their activity is regulated by guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GAPs), providing activation and inactivation of these...
12.
Kim J, Choi K, Hong C, Park H, Choi E, Kim Y, et al.
Free Radic Biol Med
. 2017 Jul;
112:69-83.
PMID: 28712859
Dysregulation of reactive oxygen species (ROS) levels is implicated in the pathogenesis of several diseases, including cancer. However, the molecular mechanisms for ROS in tumorigenesis have not been well established....
13.
Kim J, Kwon H, Wu G, Park Y, Lee J, Kim J, et al.
Free Radic Biol Med
. 2016 Dec;
103:57-68.
PMID: 27974245
Reactive oxygen species (ROS) produced by many kinds of stimuli are essential for cellular signaling including cell proliferation. The dysregulation of ROS, therefore, is related to a variety of diseases...
14.
Kim J, Kim M, Choi W, Moon M, Kim H, Lee J, et al.
J Cell Physiol
. 2016 Aug;
232(5):1104-1113.
PMID: 27575935
In canonical pathway, Wnt3A has been known to stabilize β-catenin through the dissociation between β-catenin and glycogen synthase kinase-3β (GSK-3β) that suppresses the phosphorylation and degradation of β-catenin. In non-canonical...
15.
Kim H, Kim J, Moon M, Park S, Park J
J Biol Chem
. 2013 Nov;
289(3):1429-40.
PMID: 24240172
Transforming growth factor (TGF)-β1 plays several roles in a variety of cellular functions. TGF-β1 transmits its signal through Smad transcription factor-dependent and -independent pathways. It was reported that TGF-β1 activates...
16.
Moon M, Kim H, Li Y, Kim J, Jeon Y, Won H, et al.
Cell Signal
. 2013 May;
25(9):1861-9.
PMID: 23707391
Fibrillar amyloid-beta (fAβ) peptide causes neuronal cell death, which is known as Alzheimer's disease. One of the mechanisms for neuronal cell death is the activation of microglia which releases toxic...
17.
Moon M, Kim H, Kim J, Lee J, Kim J, Kim S, et al.
J Cell Physiol
. 2013 Apr;
228(11):2119-26.
PMID: 23559363
Transforming growth factor (TGF)-β1 regulates diverse cellular functions. Particularly, TGF-β1 induces monocyte migration to sites of injury or inflammation in early period, whereas TGF-β1 inhibits cell migration in late phase....
18.
Li Y, Kim J, Kim H, Moon M, Lee J, Kim J, et al.
Free Radic Biol Med
. 2012 Feb;
52(9):1796-805.
PMID: 22330068
Phagocytic NADPH oxidase plays a critical role in superoxide generation in macrophage cells. Small GTPases, including Rac1 and Rac2, have been implicated in the regulation of NADPH oxidase activity. Rap1,...
19.
Kim J, Moon M, Kim H, Li Y, Song D, Kim J, et al.
J Biol Chem
. 2011 Dec;
287(7):5145-55.
PMID: 22194606
Phagocytosis occurs primarily through two main processes in macrophages: the Fcγ receptor- and the integrin αMβ2-mediated processes. Complement C3bi-opsonized particles are known to be engulfed through integrin αMβ2-mediated process, which...
20.
Jeon C, Moon M, Kim J, Kim H, Kim J, Li Y, et al.
J Neurochem
. 2011 Nov;
120(5):684-98.
PMID: 22035369
cAMP induces neurite outgrowth in the rat pheochromocytoma cell line 12 (PC12). In particular, di-butyric cAMP (db-cAMP) induces a greater number of primary processes with shorter length than the number...