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Jae-Chul Pyun

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Articles 132
Citations 460
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Recent Articles
1.
Jung J, Sung J, Kwon S, Bae H, Kang M, Jose J, et al.
RSC Med Chem . 2025 Feb; PMID: 39990164
Fv-antibodies targeting the transmembrane protease serine 2 (TMPRSS2) were screened from an Fv-antibody library for inhibiting SARS-CoV-2 infection. Fv-antibodies were derived from the variable region of heavy-chain immunoglobulin G (IgG),...
2.
Park J, Kwon S, Kim M, Song Z, Bae H, Kang M, et al.
Biosens Bioelectron . 2025 Feb; 277:117274. PMID: 39987657
A capacitive-localized plasmon surface resonance (LSPR) dual-mode biosensor was developed using gold (Au) nanoislands modified on an Au interdigitated electrode (IDE). Au nanoislands were deposited through repeated thermal dewetting to...
3.
Bae H, Jung J, Sung J, Kwon S, Kang M, Jose J, et al.
Int J Biol Macromol . 2025 Feb; 304(Pt 1):140770. PMID: 39922350
Deoxyribonuclease (DNase) I inhibitors have been developed based on proteins, nucleotides and synthetic compounds. In this work, amino acid sequences with the activity of DNase I inhibitor were screened from...
4.
Yun T, Park J, Kim H, Shin M, Kang M, Park M, et al.
ACS Appl Bio Mater . 2025 Jan; 8(1):609-616. PMID: 39743741
For the medical diagnosis of sepsis, it is crucial to differentiate infectious inflammation from noninfectious symptoms to prevent acute aggravation. Herein, a diagnosis for early stage sepsis was performed using...
5.
Hwang H, Kim J, Kim T, Han Y, Choi D, Cho S, et al.
BMC Cancer . 2024 Dec; 24(1):1557. PMID: 39702014
Background: Hepatocellular carcinoma (HCC) stands as the sixth most prevalent cancer globally, presenting a substantial health challenge, particularly due to late-stage diagnoses that limit treatment effectiveness. Sorafenib, a multi-kinase inhibitor,...
6.
Jung J, Kwon S, Sung J, Bae H, Kang M, Jose J, et al.
ACS Pharmacol Transl Sci . 2024 Dec; 7(12):3914-3920. PMID: 39698273
For the prevention of SARS-CoV-2 infection, four Fv-antibodies with binding affinity for the ACE2 receptor were screened from an Fv-antibody library. The screened Fv-antibodies were expressed as soluble proteins and...
7.
Jung J, Kim T, Park J, Kwon S, Sung J, Kang M, et al.
J Mater Chem B . 2024 Dec; 13(4):1383-1394. PMID: 39668674
In this study, the vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was developed using ferritin complexes with the immunogenic sequences screened against the SARS-CoV-2 spike protein (SP) from...
8.
Sung J, Jung J, Kwon S, Bae H, Kang M, Jose J, et al.
Biosens Bioelectron . 2024 Nov; 270:116980. PMID: 39608279
Migraine is known to be caused by calcitonin gene-related peptide (CGRP), prompting the need for quantitative analysis of CGRP for the clinical treatment of monoclonal antibodies targeting CGRP. Since CGRP...
9.
Song Z, Jung J, Kim T, Park J, Song H, Kang M, et al.
ACS Appl Mater Interfaces . 2024 Nov; 16(46):63255-63267. PMID: 39501653
Parylene-like films obtained via the plasma decomposition of parylene precursors with functional groups (amino and formyl) are proposed as an alternative to those obtained via the thermal method. To analyze...
10.
Han Y, Kim S, Park T, Hwang H, Park S, Kim J, et al.
Microbiol Spectr . 2024 Sep; 12(11):e0158324. PMID: 39291996
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants presents challenges in global efforts to transition from the pandemic to an endemic stage. The spike protein of the...