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Jae-Chul Pyun

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Articles 132
Citations 460
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Recent Articles
11.
Jung J, Sung J, Kwon S, Bae H, Kang M, Jose J, et al.
RSC Med Chem . 2024 Sep; PMID: 39290379
Fv-antibodies targeting the proprotein convertase (PPC) region of the SARS-CoV-2 spike protein (SP) were screened from an Fv-antibody library to inhibit SARS-CoV-2 infection. Two selected Fv-antibodies were expressed as soluble...
12.
Sung J, Jung J, Kim T, Kwon S, Bae H, Kang M, et al.
Bioconjug Chem . 2024 Aug; 35(9):1324-1334. PMID: 39197031
Inhibitors of the epithermal growth factor receptor (EGFR) were screened from an autodisplayed Fv-antibody library using an anti-EGF antibody. The Fv-antibody library was expressed on the outer membrane of ,...
13.
Kim T, Park J, Jung J, Sung J, Kwon S, Bae H, et al.
J Mater Chem B . 2024 Mar; 12(15):3751-3763. PMID: 38532694
In this study, a one-step immunoassay for porcine epidemic diarrhea virus (PEDV) based on Fv-antibodies and switching peptides was developed, and the assay results of PEDV were obtained by just...
14.
Sung J, Han Y, Yun T, Jung J, Kim T, Piccinini F, et al.
Int J Biol Macromol . 2024 Mar; 265(Pt 1):130854. PMID: 38484814
Monocarboxylate transporter-1 (MCT-1) inhibitors were screened from the Fv-antibody library, which contained complementary determining region 3 with randomized amino acid sequences (11 residues) through site-directed mutagenesis. Fv-antibodies against MCT-1 were...
15.
Bong J, Dombovski A, Birus R, Cho S, Lee M, Pyun J, et al.
J Colloid Interface Sci . 2024 Feb; 663:227-237. PMID: 38401443
Outer membrane vesicle-functionalized nanoparticles (OMV-NPs) have attracted significant interest, especially regarding drug delivery applications and vaccines. Here, we report on novel OMV-NPs by applying bioorthogonal click reaction for encapsulating gold...
16.
Piccinini F, Drudi L, Pyun J, Lee M, Kwak B, Ku B, et al.
Front Bioeng Biotechnol . 2024 Feb; 12:1339723. PMID: 38357706
In several fields, the process of fusing multiple two-dimensional (2D) closed lines is an important step. For instance, this is fundamental in histology and oncology in general. The treatment of...
17.
Cho S, Kim W, Yoo D, Han Y, Hwang H, Kim S, et al.
Sci Rep . 2024 Jan; 14(1):1751. PMID: 38243049
Hepatocellular carcinoma (HCC) is the fifth leading cause of cancer-related mortality worldwide. Programmed cell death ligand-1 (PD-L1) is an immune checkpoint protein that binds to programmed cell death-1 (PD-1), which...
18.
Sung J, Kim S, Jung J, Kim T, Kwon S, Bae H, et al.
ACS Pharmacol Transl Sci . 2024 Jan; 7(1):150-160. PMID: 38230273
Serotonin-like mimotopes were screened from the Fv-antibody library to be used as inhibitors against monoamine oxidase A (MAO-A). The Fv-antibody [corresponding to the V region of immunoglobulin G (IgG)] consists...
19.
Sung J, Jung J, Hwang H, Bong J, Kang M, Jose J, et al.
ACS Pharmacol Transl Sci . 2023 Dec; 6(12):1945-1957. PMID: 38093831
Pancreatic ribonuclease A (RNase A) inhibitors were screened from an autodisplayed Fv-antibody library, which was prepared by randomizing amino acid sequences of the third complementary-determining region (CDR3) within the heavy...
20.
Park J, Kim H, Kim M, Song Z, Kang M, Son D, et al.
ACS Appl Mater Interfaces . 2023 Nov; PMID: 38019055
A defect-passivated photosensor based on cesium lead bromide (CsPbBr) perovskite quantum dots (QD) was fabricated using parylene films, and the photosensor was applied for the microbial detection. The CsPbBr perovskite...