Jada C Domingue
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Explore the profile of Jada C Domingue including associated specialties, affiliations and a list of published articles.
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11
Citations
218
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Recent Articles
1.
Namasivayam S, Tilves C, Ding H, Wu S, Domingue J, Ruiz-Bedoya C, et al.
Gut Microbes
. 2024 May;
16(1):2353394.
PMID: 38743047
Exposing C-section infants to the maternal vaginal microbiome, coined "vaginal seeding", partially restores microbial colonization. However, whether vaginal seeding decreases metabolic disease risk is unknown. Therefore, we assessed the effect...
2.
Drewes J, Chen J, Markham N, Knippel R, Domingue J, Tam A, et al.
Cancer Discov
. 2022 Jun;
12(8):1873-1885.
PMID: 35678528
Significance: Colorectal cancer is a leading cause of cancer and cancer-related deaths worldwide, with a multifactorial etiology that likely includes procarcinogenic bacteria. Using human colon cancer specimens, culturing, and murine...
3.
Shaikh F, Gills J, Mohammad F, White J, Stevens C, Ding H, et al.
Cancer Immunol Immunother
. 2022 Feb;
71(10):2405-2420.
PMID: 35217892
Human gut microbial species found to associate with clinical responses to immune checkpoint inhibitors (ICIs) are often tested in mice using fecal microbiota transfer (FMT), wherein tumor responses in recipient...
4.
Queen J, Domingue J, White J, Stevens C, Udayasuryan B, Nguyen T, et al.
mBio
. 2022 Feb;
13(1):e0299121.
PMID: 35130731
Fusobacteria are commonly associated with human colorectal cancer (CRC), but investigations are hampered by the absence of a stably colonized murine model. Further, Fusobacterium nucleatum subspecies isolated from human CRC...
5.
Domingue J, Drewes J, Merlo C, Housseau F, Sears C
Mucosal Immunol
. 2020 Mar;
13(3):413-422.
PMID: 32112046
The impact of the human microbiome on health and disease is of utmost importance and has been studied intensively in recent years. Microbes promote immune system development and are essential...
6.
Chen J, Domingue J, Sears C
Semin Immunol
. 2017 Aug;
32:25-34.
PMID: 28822617
The human microbiota is a complex ecosystem of diverse microorganisms consisting of bacteria, viruses, and fungi residing predominantly in epidermal and mucosal habitats across the body, such as skin, oral...
7.
Domingue J, Ao M, Sarathy J, Rao M
Am J Physiol Cell Physiol
. 2016 Aug;
311(5):C777-C792.
PMID: 27558159
Bile acids are known to initiate intricate signaling events in a variety of tissues, primarily in the liver and gastrointestinal tract. Of the known bile acids, only the 7α-dihydroxy species,...
8.
Ao M, Domingue J, Khan N, Javed F, Osmani K, Sarathy J, et al.
Am J Physiol Cell Physiol
. 2016 Apr;
310(11):C1010-23.
PMID: 27076617
Bile acids (BAs) play a complex role in colonic fluid secretion. We showed that dihydroxy BAs, but not the monohydroxy BA lithocholic acid (LCA), stimulate Cl(-) secretion in human colonic...
9.
Domingue J, Rao M
Am J Physiol Cell Physiol
. 2015 May;
309(1):C11-3.
PMID: 25972453
No abstract available.
10.
Domingue J, Ao M, Sarathy J, George A, Alrefai W, Nelson D, et al.
Physiol Rep
. 2014 Sep;
2(9).
PMID: 25263207
The Human Embryonic Kidney 293 cell line (HEK-293) readily lends itself to genetic manipulation and is a common tool for biologists to overexpress proteins of interest and study their function...