Jacques Weill
Overview
Explore the profile of Jacques Weill including associated specialties, affiliations and a list of published articles.
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47
Citations
3007
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Recent Articles
1.
Siffo S, Gomes Pio M, Martinez E, Lachlan K, Walker J, Weill J, et al.
Endocrine
. 2022 Dec;
80(1):47-53.
PMID: 36547798
Thyroglobulin (TG), the predominant glycoprotein of the thyroid gland, functions as matrix protein in thyroid hormonegenesis. TG deficiency results in thyroid dyshormonogenesis. These variants produce a heterogeneous spectrum of congenital...
2.
Parent C, Lespagnol E, Berthoin S, Tagougui S, Heyman J, Stuckens C, et al.
Can J Diabetes
. 2022 Nov;
47(2):124-132.
PMID: 36411182
Objectives: Ever since the first research on barriers to physical activity (PA) highlighting fear of hypoglycemia as a major barrier, many studies have attempted to understand their demographic and behavioural...
3.
Paccoud R, Saint-Laurent C, Piccolo E, Tajan M, Dortignac A, Pereira O, et al.
Sci Transl Med
. 2021 Apr;
13(591).
PMID: 33910978
Insulin resistance is a key event in type 2 diabetes onset and a major comorbidity of obesity. It results from a combination of fat excess-triggered defects, including lipotoxicity and metaflammation,...
4.
Baron M, Maillet J, Huyvaert M, Dechaume A, Boutry R, Loiselle H, et al.
Nat Med
. 2019 Nov;
25(11):1733-1738.
PMID: 31700171
The G-protein-coupled receptor accessory protein MRAP2 is implicated in energy control in rodents, notably via the melanocortin-4 receptor. Although some MRAP2 mutations have been described in people with obesity, their...
5.
Montagne L, Derhourhi M, Piton A, Toussaint B, Durand E, Vaillant E, et al.
Mol Metab
. 2018 May;
13:1-9.
PMID: 29784605
Objective: The molecular diagnosis of extreme forms of obesity, in which accurate detection of both copy number variations (CNVs) and point mutations, is crucial for an optimal care of the...
6.
Siffo S, Adrover E, Citterio C, Miras M, Balbi V, Chiesa A, et al.
Mol Cell Endocrinol
. 2017 Dec;
473:1-16.
PMID: 29275168
Thyroid dyshormonogenesis due to thyroglobulin (TG) gene mutations have an estimated incidence of approximately 1 in 100,000 newborns. The clinical spectrum ranges from euthyroid to mild or severe hypothyroidism. Up...
7.
Tamborlane W, Laffel L, Weill J, Gordat M, Neubacher D, Retlich S, et al.
Pediatr Diabetes
. 2017 Nov;
19(4):640-648.
PMID: 29171139
Objective: To identify the dose of the dipeptidyl peptidase-4 (DPP-4) inhibitor linagliptin in pediatric patients with type 2 diabetes (T2D). Methods: Double-blind, randomized, controlled parallel group study comparing linagliptin 1...
8.
Bonnefond A, Yengo L, Dechaume A, Canouil M, Castelain M, Roger E, et al.
BMC Med
. 2017 Feb;
15(1):37.
PMID: 28228143
Background: Salivary (AMY1) and pancreatic (AMY2) amylases hydrolyze starch. Copy number of AMY1A (encoding AMY1) was reported to be higher in populations with a high-starch diet and reduced in obese...
9.
Balazard F, Le Fur S, Valtat S, Valleron A, Bougneres P, Thevenieau D, et al.
BMC Public Health
. 2016 Sep;
16(1):1021.
PMID: 27682602
Background: The incidence of childhood type 1 diabetes (T1D) incidence is rising in many countries, supposedly because of changing environmental factors, which are yet largely unknown. The purpose of the...
10.
Morandi A, Bonnefond A, Lobbens S, Yengo L, Del Giudice E, Grandone A, et al.
J Clin Endocrinol Metab
. 2016 Sep;
101(11):4244-4250.
PMID: 27588439
Context: Young-onset obesity is strongly associated with the early development of type 2 diabetes (T2D). Genetic risk scores (GRSs) related to T2D might help predicting the early impairment of glucose...