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Jacob Lemieux

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Articles 15
Citations 1318
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Recent Articles
1.
Patel S, Leeman B, Botros P, Folta J, Shahid D, Rocque A, et al.
Res Sq . 2024 Dec; PMID: 39678346
As of May 2023, the public health emergency of COVID-19 was lifted across the globe. However, SARS-CoV-2 infections continue to be recorded worldwide. This situation has been attributed to the...
2.
Klontz E, Chowdhury N, Holbrook N, Solomon I, Telford 3rd S, Aliota M, et al.
Viruses . 2024 Nov; 16(11). PMID: 39599768
Powassan virus (POWV) is an emerging tick-borne virus that causes severe meningoencephalitis in the United States, Canada, and Russia. Serology is generally the preferred diagnostic modality, but PCR on cerebrospinal...
3.
Hunt M, Hinrichs A, Anderson D, Karim L, Dearlove B, Knaggs J, et al.
bioRxiv . 2024 May; PMID: 38746185
The SARS-CoV-2 genome occupies a unique place in infection biology - it is the most highly sequenced genome on earth (making up over 20% of public sequencing datasets) with fine...
4.
Turner S, Alisoltani A, Bratt D, Cohen-Lavi L, Dearlove B, Drosten C, et al.
Emerg Infect Dis . 2023 Apr; 29(5). PMID: 37054986
Since late 2020, SARS-CoV-2 variants have regularly emerged with competitive and phenotypic differences from previously circulating strains, sometimes with the potential to escape from immunity produced by prior exposure and...
5.
Adams G, Moreno G, Petros B, Uddin R, Levine Z, Kotzen B, et al.
medRxiv . 2023 Jan; PMID: 36656774
The US experienced an early and severe respiratory syncytial virus (RSV) surge in autumn 2022. Despite the pressure this has put on hospitals and care centers, the factors promoting the...
6.
Regan J, Flynn J, Choudhary M, Uddin R, Lemieux J, Boucau J, et al.
Open Forum Infect Dis . 2022 Feb; 9(3):ofac022. PMID: 35169591
We assessed the ability of the BinaxNow rapid test to detect severe acute respiratory syndrome coronavirus 2 antigen from 4 individuals with Omicron and Delta infections. We performed serial dilutions...
7.
Piantadosi A, Mukerji S, Ye S, Leone M, Freimark L, Park D, et al.
mBio . 2021 Sep; 12(4):e0114321. PMID: 34465023
Meningitis and encephalitis are leading causes of central nervous system (CNS) disease and often result in severe neurological compromise or death. Traditional diagnostic workflows largely rely on pathogen-specific tests, sometimes...
8.
Normandin E, Solomon I, Zamirpour S, Lemieux J, Freije C, Mukerji S, et al.
Open Forum Infect Dis . 2020 Oct; 7(10):ofaa392. PMID: 33094116
Background: Powassan virus (POWV) is an emerging cause of severe encephalitis; very little is known about human pathogenicity due to challenges in diagnosis and viral RNA recovery. We present 3...
9.
Conklin J, Frosch M, Mukerji S, Rapalino O, Maher M, Schaefer P, et al.
medRxiv . 2020 Aug; PMID: 32743599
Importance: Microvascular lesions are common in patients with severe COVID-19. Radiologic-pathologic correlation in one case suggests a combination of microvascular hemorrhagic and ischemic lesions that may reflect an underlying hypoxic...
10.
Piantadosi A, Kanjilal S, Ganesh V, Khanna A, Hyle E, Rosand J, et al.
Clin Infect Dis . 2017 Oct; 66(5):789-792. PMID: 29020227
We describe a patient with severe and progressive encephalitis of unknown etiology. We performed rapid metagenomic sequencing from cerebrospinal fluid and identified Powassan virus, an emerging tick-borne flavivirus that has...