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Jacob Elkahal

Explore the profile of Jacob Elkahal including associated specialties, affiliations and a list of published articles. Areas
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Citations 10
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Recent Articles
1.
Miyara S, Adler M, Umansky K, Haussler D, Bassat E, Divinsky Y, et al.
Cell Syst . 2025 Feb; :101198. PMID: 39970910
Fibrosis remains a major unmet medical need. Simplifying principles are needed to better understand fibrosis and to yield new therapeutic approaches. Fibrosis is driven by myofibroblasts that interact with macrophages....
2.
Aviel G, Elkahal J, Umansky K, Bueno-Levy H, Petrover Z, Kotlovski Y, et al.
Nat Cardiovasc Res . 2024 Aug; 3(9):1049-1066. PMID: 39215106
Myocardial injury may ultimately lead to adverse ventricular remodeling and development of heart failure (HF), which is a major cause of morbidity and mortality worldwide. Given the slow pace and...
3.
Zhang L, Elkahal J, Wang T, Rimmer R, Genzelinakh A, Bassat E, et al.
Nat Cardiovasc Res . 2024 Aug; 3(8):915-932. PMID: 39196027
Senescence plays a key role in various physiological and pathological processes. We reported that injury-induced transient senescence correlates with heart regeneration, yet the multi-omics profile and molecular underpinnings of regenerative...
4.
Shakked A, Petrover Z, Aharonov A, Ghiringhelli M, Umansky K, Kain D, et al.
Nat Cardiovasc Res . 2023 Nov; 2(4):383-398. PMID: 37974970
Cardiomyocyte proliferation and dedifferentiation have fueled the field of regenerative cardiology in recent years, whereas the reverse process of redifferentiation remains largely unexplored. Redifferentiation is characterized by the restoration of...
5.
Kozlovski S, Regev O, Sapoznikov A, Kizner M, Achdout H, Petrovich-Kopitman E, et al.
Front Immunol . 2023 Mar; 13:1041552. PMID: 36895258
αLβ2 (LFA-1) mediated interactions with ICAM-1 and ICAM-2 predominate leukocyte-vascular interactions, but their functions in extravascular cell-cell communications is still debated. The roles of these two ligands in leukocyte trafficking,...