Kfir Baruch Umansky
Overview
Explore the profile of Kfir Baruch Umansky including associated specialties, affiliations and a list of published articles.
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10
Citations
592
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Recent Articles
1.
Aviel G, Elkahal J, Umansky K, Bueno-Levy H, Petrover Z, Kotlovski Y, et al.
Nat Cardiovasc Res
. 2024 Aug;
3(9):1049-1066.
PMID: 39215106
Myocardial injury may ultimately lead to adverse ventricular remodeling and development of heart failure (HF), which is a major cause of morbidity and mortality worldwide. Given the slow pace and...
2.
Pianca N, Sacchi F, Umansky K, Chirivi M, Iommarini L, Da Pra S, et al.
Nat Cardiovasc Res
. 2024 Aug;
1(7):617-633.
PMID: 39196236
In mammals, the physiological activation of the glucocorticoid receptor (GR) by glucocorticoids (GCs) promotes the maturation of cardiomyocytes during late gestation, but the effect on postnatal cardiac growth and regenerative...
3.
Zhang L, Elkahal J, Wang T, Rimmer R, Genzelinakh A, Bassat E, et al.
Nat Cardiovasc Res
. 2024 Aug;
3(8):915-932.
PMID: 39196027
Senescence plays a key role in various physiological and pathological processes. We reported that injury-induced transient senescence correlates with heart regeneration, yet the multi-omics profile and molecular underpinnings of regenerative...
4.
Aharonov A, Shakked A, Umansky K, Savidor A, Genzelinakh A, Kain D, et al.
Nat Cell Biol
. 2020 Oct;
22(11):1346-1356.
PMID: 33046882
Cardiomyocyte loss after injury results in adverse remodelling and fibrosis, inevitably leading to heart failure. The ERBB2-Neuregulin and Hippo-YAP signalling pathways are key mediators of heart regeneration, yet the crosstalk...
5.
Baehr A, Umansky K, Bassat E, Jurisch V, Klett K, Bozoglu T, et al.
Circulation
. 2020 Jun;
142(9):868-881.
PMID: 32508131
Background: Ischemic heart diseases are leading causes of death and reduced life quality worldwide. Although revascularization strategies significantly reduce mortality after acute myocardial infarction (MI), a large number of patients...
6.
Yifa O, Weisinger K, Bassat E, Li H, Kain D, Barr H, et al.
JCI Insight
. 2019 Nov;
4(22).
PMID: 31723055
The adult mammalian heart regenerates poorly after injury and, as a result, ischemic heart diseases are among the leading causes of death worldwide. The recovery of the injured heart is...
7.
Sarig R, Rimmer R, Bassat E, Zhang L, Umansky K, Lendengolts D, et al.
Circulation
. 2019 May;
139(21):2491-2494.
PMID: 31107623
No abstract available.
8.
Bassat E, Eid Mutlak Y, Genzelinakh A, Shadrin I, Umansky K, Yifa O, et al.
Nature
. 2017 Jun;
547(7662):179-184.
PMID: 28581497
The adult mammalian heart is non-regenerative owing to the post-mitotic nature of cardiomyocytes. The neonatal mouse heart can regenerate, but only during the first week of life. Here we show...
9.
Umansky K, Feldmesser E, Groner Y
Genom Data
. 2015 Dec;
6:120-2.
PMID: 26697350
In response to muscle damage the muscle adult stem cells are activated and differentiate into myoblasts that regenerate the damaged tissue. We have recently showed that following myopathic damage the...
10.
Umansky K, Gruenbaum-Cohen Y, Tsoory M, Feldmesser E, Goldenberg D, Brenner O, et al.
PLoS Genet
. 2015 Aug;
11(8):e1005457.
PMID: 26275053
Following myonecrosis, muscle satellite cells proliferate, differentiate and fuse, creating new myofibers. The Runx1 transcription factor is not expressed in naïve developing muscle or in adult muscle tissue. However, it...