Jacob E Lazarus
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Explore the profile of Jacob E Lazarus including associated specialties, affiliations and a list of published articles.
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31
Citations
814
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Recent Articles
11.
Lazarus J, Warr A, Westervelt K, Hooper D, Waldor M
Antimicrob Agents Chemother
. 2021 Sep;
65(12):e0078621.
PMID: 34491801
Serratia marcescens, a member of the order Enterobacterales, is adept at colonizing health care environments and is an important cause of invasive infections. Antibiotic resistance is a daunting problem in...
12.
Dugdale C, Anahtar M, Chiosi J, Lazarus J, McCluskey S, Ciaranello A, et al.
Open Forum Infect Dis
. 2021 Jun;
8(1):ofaa559.
PMID: 34164560
Background: Concerns about false-negative (FN) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid amplification tests (NAATs) have prompted recommendations for repeat testing if suspicion for coronavirus disease 2019 (COVID-19)...
13.
Dugdale C, Rubins D, Lee H, McCluskey S, Ryan E, Kotton C, et al.
Clin Infect Dis
. 2021 Feb;
73(12):2248-2256.
PMID: 33564833
Background: Isolation of hospitalized persons under investigation (PUIs) for coronavirus disease 2019 (COVID-19) reduces nosocomial transmission risk. Efficient evaluation of PUIs is needed to preserve scarce healthcare resources. We describe...
14.
Lazarus J, Branda J, Gandhi R, Barshak M, Zachary K, Barczak A
Open Forum Infect Dis
. 2020 Jul;
7(6):ofaa166.
PMID: 32617367
is a ubiquitous environmental saprophyte with worldwide distribution. Commonly found in soil and decomposing organic material [1, 2], can also be isolated from drinking water [3] and indoor and outdoor...
15.
Lazarus J, Warr A, Kuehl C, Giorgio R, Davis B, Waldor M
Appl Environ Microbiol
. 2019 Jun;
85(16).
PMID: 31201277
Despite the advent of new techniques for genetic engineering of bacteria, allelic exchange through homologous recombination remains an important tool for genetic analysis. Currently, -based vector systems are often used...
16.
Park J, Helble J, Lazarus J, Yang G, Blondel C, Doench J, et al.
iScience
. 2018 Dec;
11:71-84.
PMID: 30590252
The invasion of Chlamydia trachomatis, an obligate intracellular bacterium, into epithelial cells is driven by a complex interplay of host and bacterial factors. To comprehensively define the host genes required...
17.
Pacheco A, Lazarus J, Sit B, Schmieder S, Lencer W, Blondel C, et al.
mBio
. 2018 Jun;
9(3).
PMID: 29921669
Enterohemorrhagic (EHEC) has two critical virulence factors-a type III secretion system (T3SS) and Shiga toxins (Stxs)-that are required for the pathogen to colonize the intestine and cause diarrheal disease. Here,...
18.
Hillis J, Ruan A, Lazarus J, Montgomery M, Berkowitz A
Neurology
. 2018 May;
90(19):e1724-e1729.
PMID: 29735779
No abstract available.
19.
Jain N, Doyon J, Lazarus J, Schaefer I, Johncilla M, Agoston A, et al.
J Gen Intern Med
. 2018 Mar;
33(5):769-772.
PMID: 29532302
Biologic agents are effective treatments for rheumatoid arthritis but are associated with important risks, including severe infections. Tumor Necrosis Factor (TNF) α inhibitors are known to increase the risk of...
20.
Nirschl J, Magiera M, Lazarus J, Janke C, Holzbaur E
Cell Rep
. 2016 Mar;
14(11):2637-52.
PMID: 26972003
Motor-cargo recruitment to microtubules is often the rate-limiting step of intracellular transport, and defects in this recruitment can cause neurodegenerative disease. Here, we use in vitro reconstitution assays with single-molecule...