Jacob D Painter
Overview
Explore the profile of Jacob D Painter including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
269
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Recent Articles
1.
Hurrell B, Helou D, Howard E, Painter J, Shafiei-Jahani P, Sharpe A, et al.
Nat Commun
. 2022 Aug;
13(1):5118.
PMID: 36045140
Regulatory T (Treg) cells are central to limit immune responses to allergens. Here we show that PD-L2 deficiency prevents the induction of tolerance to ovalbumin and control of airway hyperreactivity,...
2.
Helou D, Quach C, Fung M, Painter J, Hurrell B, Loh Y, et al.
J Allergy Clin Immunol
. 2022 Aug;
151(2):526-538.e8.
PMID: 35963455
Background: Neutrophilic asthma is associated with disease severity and corticosteroid insensitivity. Novel therapies are required to manage this life-threatening asthma phenotype. Programmed cell death protein-1 (PD-1) is a key homeostatic...
3.
Galle-Treger L, Helou D, Quach C, Howard E, Hurrell B, Aleman Muench G, et al.
Nat Commun
. 2022 Mar;
13(1):1440.
PMID: 35301333
There has been a global increase in rates of obesity with a parallel epidemic of non-alcoholic fatty liver disease (NAFLD). Autophagy is an essential mechanism involved in the degradation of...
4.
Hurrell B, Helou D, Shafiei-Jahani P, Howard E, Painter J, Quach C, et al.
J Allergy Clin Immunol
. 2021 Oct;
149(5):1628-1642.e10.
PMID: 34673048
Background: Cannabinoids modulate the activation of immune cells and physiologic processes in the lungs. Group 2 innate lymphoid cells (ILC2s) are central players in type 2 asthma, but how cannabinoids...
5.
Howard E, Hurrell B, Helou D, Quach C, Painter J, Shafiei-Jahani P, et al.
Front Immunol
. 2021 Sep;
12:733136.
PMID: 34531874
While pulmonary ILC2s represent one of the major tissue-resident innate lymphoid cell populations at steady state and are key drivers of cytokine secretion in their occupational niche, their role in...
6.
Painter J, Akbari O
Front Immunol
. 2021 Sep;
12:727008.
PMID: 34489979
Type 2 innate lymphoid cells (ILC2) are the innate counterparts of Th2 cells and are critically involved in the maintenance of homeostasis in a variety of tissues. Instead of expressing...
7.
Helou D, Shafiei-Jahani P, Hurrell B, Painter J, Quach C, Howard E, et al.
J Allergy Clin Immunol
. 2021 Jun;
149(1):223-236.e6.
PMID: 34144112
Background: Type 2 innate lymphoid cells (ILC2s) are relevant players in type 2 asthma. They initiate eosinophil infiltration and airway hyperreactivity (AHR) through cytokine secretion. Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1)...
8.
Shafiei-Jahani P, Helou D, Hurrell B, Howard E, Quach C, Painter J, et al.
Nat Commun
. 2021 May;
12(1):2526.
PMID: 33953190
The prevalence of asthma and airway hyperreactivity (AHR) is increasing at an alarming rate. Group 2 innate lymphoid cells (ILC2s) are copious producers of type 2 cytokines, which leads to...
9.
Shafiei-Jahani P, Helou D, Hurrell B, Galle-Treger L, Howard E, Quach C, et al.
Mucosal Immunol
. 2021 Mar;
14(4):899-911.
PMID: 33731828
Allergic asthma is a chronic inflammatory disorder associated with airway hyperreactivity (AHR) whose global prevalence is increasing at an alarming rate. Group 2 innate lymphoid cells (ILC2s) and T helper...
10.
Hurrell B, Howard E, Galle-Treger L, Helou D, Shafiei-Jahani P, Painter J, et al.
Front Immunol
. 2020 Nov;
11:542818.
PMID: 33193309
Asthma is a heterogeneous airway inflammatory disease characterized by increased airway hyperreactivity (AHR) to specific and unspecific stimuli. Group 2 innate lymphoid cells (ILC2)s are type-2 cytokine secreting cells capable...