Pejman Soroosh
Overview
Explore the profile of Pejman Soroosh including associated specialties, affiliations and a list of published articles.
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45
Citations
2531
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Recent Articles
1.
Zhang P, Liu J, Lee A, Tsaur I, Ohira M, Duong V, et al.
Cell Metab
. 2024 Sep;
36(10):2341-2354.e6.
PMID: 39317186
The exponential rise in metabolic dysfunction-associated steatotic liver disease (MASLD) parallels the ever-increasing consumption of energy-dense diets, underscoring the need for effective MASLD-resolving drugs. MASLD pathogenesis is linked to obesity,...
2.
Lipid-associated macrophages' promotion of fibrosis resolution during MASH regression requires TREM2
Ganguly S, Rosenthal S, Ishizuka K, Troutman T, Rohm T, Khader N, et al.
Proc Natl Acad Sci U S A
. 2024 Aug;
121(35):e2405746121.
PMID: 39172787
While macrophage heterogeneity during metabolic dysfunction-associated steatohepatitis (MASH) has been described, the fate of these macrophages during MASH regression is poorly understood. Comparing macrophage heterogeneity during MASH progression vs regression,...
3.
Quach C, Helou D, Li M, Hurrell B, Howard E, Shafiei-Jahani P, et al.
Cell Rep
. 2023 Aug;
42(8):112990.
PMID: 37590140
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe clinical disorders that mainly develop from viral respiratory infections, sepsis, and chest injury. Antigen-presenting cells play a pivotal...
4.
Liu X, Lam K, Zhao H, Sakane S, Kim H, Eguileor A, et al.
STAR Protoc
. 2023 Jul;
4(3):102391.
PMID: 37405925
Here, we present a protocol for isolating human hepatocytes and neural progenitor cells from normal and nonalcoholic steatohepatitis livers. We describe steps for perfusion for scaled-up liver cell isolation and...
5.
Movassagh H, Prunicki M, Kaushik A, Zhou X, Dunham D, Smith E, et al.
Allergy
. 2023 Mar;
78(7):1922-1933.
PMID: 36929161
Background: The impact of exposure to air pollutants, such as fine particulate matter (PM), on the immune system and its consequences on pediatric asthma, are not well understood. We investigated...
6.
Helou D, Quach C, Fung M, Painter J, Hurrell B, Loh Y, et al.
J Allergy Clin Immunol
. 2022 Aug;
151(2):526-538.e8.
PMID: 35963455
Background: Neutrophilic asthma is associated with disease severity and corticosteroid insensitivity. Novel therapies are required to manage this life-threatening asthma phenotype. Programmed cell death protein-1 (PD-1) is a key homeostatic...
7.
Galle-Treger L, Helou D, Quach C, Howard E, Hurrell B, Aleman Muench G, et al.
Nat Commun
. 2022 Mar;
13(1):1440.
PMID: 35301333
There has been a global increase in rates of obesity with a parallel epidemic of non-alcoholic fatty liver disease (NAFLD). Autophagy is an essential mechanism involved in the degradation of...
8.
Howard E, Hurrell B, Helou D, Quach C, Painter J, Shafiei-Jahani P, et al.
Front Immunol
. 2021 Sep;
12:733136.
PMID: 34531874
While pulmonary ILC2s represent one of the major tissue-resident innate lymphoid cell populations at steady state and are key drivers of cytokine secretion in their occupational niche, their role in...
9.
Xian H, Liu Y, Rundberg Nilsson A, Gatchalian R, Crother T, Tourtellotte W, et al.
Immunity
. 2021 Jun;
54(7):1463-1477.e11.
PMID: 34115964
Acute respiratory distress syndrome (ARDS), an inflammatory condition with high mortality rates, is common in severe COVID-19, whose risk is reduced by metformin rather than other anti-diabetic medications. Detecting of...
10.