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Jacob Campbell

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Articles 13
Citations 68
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Recent Articles
1.
Pradeep S, Thirunavukkarasu M, Accorsi D, Swaminathan S, Lim S, Cernuda B, et al.
Biochim Biophys Acta Mol Basis Dis . 2023 Oct; 1870(1):166899. PMID: 37778482
Objectives: Ubiquitination plays a vital role in controlling vascular inflammation, cellular protein quality control, and minimizing misfolded protein toxicity. Pellino-1 (Peli1), a type of E3 ubiquitin ligase, has emerged as...
2.
Thirunavukkarasu M, Swaminathan S, Kemerley A, Pradeep S, Lim S, Accorsi D, et al.
Cells . 2023 Jun; 12(11). PMID: 37296648
Objectives: Intra-abdominal sepsis is commonly diagnosed in the surgical population and remains the second most common cause of sepsis overall. Sepsis-related mortality remains a significant burden in the intensive care...
3.
Carpenter S, Campbell J, Jayaraman V
BMJ Case Rep . 2022 Mar; 15(3). PMID: 35236689
Caecal herniation through the foramen of Winslow is an uncommon presentation of internal hernia with an estimated overall incidence of 0.02%. Even rarer still is a caecal volvulus strangulated in...
4.
Thirunavukkarasu M, Pradeep S, Ukani G, Abunnaja S, Youssef M, Accorsi D, et al.
Microvasc Res . 2022 Jan; 141:104311. PMID: 34999110
Objectives: In the United States, over 8.5 million people suffer from peripheral arterial disease (PAD). Previously we reported that Pellino-1(Peli1) gene therapy reduces ischemic damage in the myocardium and skin...
5.
Selvaraju V, Thirunavukkarasu M, Joshi M, Oriowo B, Shaikh I, Tipu Rishi M, et al.
Basic Res Cardiol . 2020 Jun; 115(4):45. PMID: 32537701
Introduction: In the present study, we aimed to explore the functional role of Pellino-1 (Peli1) in inducing neovascularization after myocardial infarction (MI) and hindlimb ischemia (HLI) using Peli1 global knockout...
6.
White C, Kyle J, Deas C, Campbell J
South Med J . 2019 Aug; 112(8):438-443. PMID: 31375841
Objectives: Urinary tract infections (UTIs) caused by extended-spectrum β-lactamase (ESBL)-producing are resistant to many conventional therapies, including third-generation cephalosporins. Carbapenems are considered first-line agents for ESBL infections, but their use...
7.
Lakshmanan R, Campbell J, Ukani G, OReilly Beringhs A, Selvaraju V, Thirunavukkarasu M, et al.
Int J Pharm . 2019 Jan; 558:177-186. PMID: 30639221
The complete loss of dermal tissue due to ischemia is a serious challenge facing clinicians. Frequently, the failure of wound healing is due to ischemic conditions prevailing at the site...
8.
Thirunavukkarasu M, Selvaraju V, Joshi M, Coca-Soliz V, Tapias L, Saad I, et al.
J Am Heart Assoc . 2018 Oct; 7(18):e007601. PMID: 30371196
Background The present study demonstrates that the ubiquitin E3 ligase, Pellino-1 (Peli1), is an important angiogenic molecule under the control of vascular endothelial growth factor (VEGF) receptor 2/Flk-1. We have...
9.
Wilson R, Selvaraju V, Lakshmanan R, Thirunavukkarasu M, Campbell J, McFadden D, et al.
J Surg Res . 2017 Nov; 220:68-78. PMID: 29180214
Background: Sepsis is a leading cause of mortality among patients in intensive care units across the USA. Thioredoxin-1 (Trx-1) is an essential 12 kDa cytosolic protein that, apart from maintaining...
10.
Haider A, Gottlich C, Khahera A, Vayalumkal S, Khan U, Arrey E, et al.
Cureus . 2017 Jun; 9(5):e1254. PMID: 28649477
Computed tomography angiography (CTA) has become an effective tool in the evaluation of patients with subarachnoid hemorrhage (SAH), but it still has limitations. Up to 15% of non-traumatic SAH cases...