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David W McFadden

Explore the profile of David W McFadden including associated specialties, affiliations and a list of published articles. Areas
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Articles 95
Citations 759
Followers 0
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Recent Articles
1.
Thirunavukkarasu M, Swaminathan S, Kemerley A, Pradeep S, Lim S, Accorsi D, et al.
Cells . 2023 Jun; 12(11). PMID: 37296648
Objectives: Intra-abdominal sepsis is commonly diagnosed in the surgical population and remains the second most common cause of sepsis overall. Sepsis-related mortality remains a significant burden in the intensive care...
2.
Campbell J, Lakshmanan R, Selvaraju V, Accorsi D, McFadden D, Maulik N, et al.
Int J Pharm . 2021 Feb; 597:120236. PMID: 33539996
Despite recent advancements, mortality due to coronary heart disease (CHD) remains high. Recently, the use of tissue-engineered grafts and scaffolds has emerged as a candidate for supporting the myocardium after...
3.
Selvaraju V, Thirunavukkarasu M, Joshi M, Oriowo B, Shaikh I, Tipu Rishi M, et al.
Basic Res Cardiol . 2020 Jun; 115(4):45. PMID: 32537701
Introduction: In the present study, we aimed to explore the functional role of Pellino-1 (Peli1) in inducing neovascularization after myocardial infarction (MI) and hindlimb ischemia (HLI) using Peli1 global knockout...
4.
Bulsara K, McFadden D
Oper Neurosurg (Hagerstown) . 2020 Jun; 19(4):351-352. PMID: 32521008
No abstract available.
5.
Katz M, Silverstein N, Coll P, Sullivan G, Mortensen E, Sachs A, et al.
Curr Probl Surg . 2019 Dec; 56(12):100647. PMID: 31837715
No abstract available.
6.
Katz M, Silverstein N, Coll P, Sullivan G, Sachs A, Gross J, et al.
Curr Probl Surg . 2019 Jun; 56(7):260-329. PMID: 31229137
No abstract available.
7.
Thirunavukkarasu M, Selvaraju V, Joshi M, Coca-Soliz V, Tapias L, Saad I, et al.
J Am Heart Assoc . 2018 Oct; 7(18):e007601. PMID: 30371196
Background The present study demonstrates that the ubiquitin E3 ligase, Pellino-1 (Peli1), is an important angiogenic molecule under the control of vascular endothelial growth factor (VEGF) receptor 2/Flk-1. We have...
8.
Saad I, Fournier C, Wilson R, Lakshmanan R, Selvaraju V, Thirunavukkarasu M, et al.
Surgery . 2018 Aug; 164(5):1077-1086. PMID: 30131176
Background: Nonhealing wounds are a continuing health problem in the United States. Overproduction of reactive oxygen species is a major causative factor behind delayed wound healing. Previously we reported that...
9.
Wilson R, Selvaraju V, Lakshmanan R, Thirunavukkarasu M, Campbell J, McFadden D, et al.
J Surg Res . 2017 Nov; 220:68-78. PMID: 29180214
Background: Sepsis is a leading cause of mortality among patients in intensive care units across the USA. Thioredoxin-1 (Trx-1) is an essential 12 kDa cytosolic protein that, apart from maintaining...
10.