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Jacob A Vorstman

Explore the profile of Jacob A Vorstman including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 364
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Recent Articles
1.
Jagesar R, Vorstman J, Kas M
J Med Internet Res . 2021 Apr; 23(4):e20996. PMID: 33825695
Background: Digital phenotyping, the measurement of human behavioral phenotypes using personal devices, is rapidly gaining popularity. Novel initiatives, ranging from software prototypes to user-ready research platforms, are innovating the field...
2.
Chawner S, Doherty J, Anney R, Antshel K, Bearden C, Bernier R, et al.
Am J Psychiatry . 2021 Jan; 178(1):77-86. PMID: 33384013
Objective: Certain copy number variants (CNVs) greatly increase the risk of autism. The authors conducted a genetics-first study to investigate whether heterogeneity in the clinical presentation of autism is underpinned...
3.
Jongs N, Penninx B, Arango C, Ayuso-Mateos J, van der Wee N, Rossum I, et al.
J Psychiatr Res . 2020 Nov; 145:302-308. PMID: 33221026
Background: Questionnaires are the current hallmark for quantifying social functioning in human clinical research. In this study, we compared self- and proxy-rated (caregiver and researcher) assessments of social functioning in...
4.
Jongs N, Jagesar R, van Haren N, Penninx B, Reus L, Visser P, et al.
Transl Psychiatry . 2020 Jul; 10(1):211. PMID: 32612118
The use of smartphone-based location data to quantify behavior longitudinally and passively is rapidly gaining traction in neuropsychiatric research. However, a standardized and validated preprocessing framework for deriving behavioral phenotypes...
5.
Arango C, Diaz-Caneja C, McGorry P, Rapoport J, Sommer I, Vorstman J, et al.
Lancet Psychiatry . 2018 May; 5(7):591-604. PMID: 29773478
Available treatment methods have shown little effect on the burden associated with mental health disorders. We review promising universal, selective, and indicated preventive mental health strategies that might reduce the...
6.
de Vrij F, Bouwkamp C, Gunhanlar N, Shpak G, Lendemeijer B, Baghdadi M, et al.
Mol Psychiatry . 2018 Jan; 24(5):757-771. PMID: 29302076
Schizophrenia is highly heritable, yet its underlying pathophysiology remains largely unknown. Among the most well-replicated findings in neurobiological studies of schizophrenia are deficits in myelination and white matter integrity; however,...
7.
Lipstein N, Verhoeven-Duif N, Michelassi F, Calloway N, van Hasselt P, Pienkowska K, et al.
J Clin Invest . 2017 Feb; 127(3):1005-1018. PMID: 28192369
Munc13 proteins are essential regulators of neurotransmitter release at nerve cell synapses. They mediate the priming step that renders synaptic vesicles fusion-competent, and their genetic elimination causes a complete block...