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Jacob A Gordon

Explore the profile of Jacob A Gordon including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 74
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Recent Articles
1.
Bashi A, Coker E, Bulusu K, Jaaks P, Crafter C, Lightfoot H, et al.
Cancer Discov . 2024 Mar; 14(5):846-865. PMID: 38456804
Significance: We present the largest cancer drug combination screen published to date with 7 × 7 concentration response matrices for 109 combinations in more than 750 cell lines, complemented by...
2.
Pandey M, Cuddihy G, Gordon J, Cox M, Wasan K
Pharmaceutics . 2021 Sep; 13(9). PMID: 34575583
There have been several studies that have linked elevated scavenger receptor class b type 1 (SR-B1) expression and activity to the development and progression of castration-resistant prostate cancer (CRPC). SR-B1...
3.
Eyford B, Singh C, Abraham T, Munro L, Choi K, Hill T, et al.
Front Mol Biosci . 2021 May; 8:687587. PMID: 34026851
[This corrects the article DOI: 10.3389/fmolb.2021.611367.].
4.
Eyford B, Singh C, Abraham T, Munro L, Choi K, Hill T, et al.
Front Mol Biosci . 2021 Apr; 8:611367. PMID: 33869275
The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment of neuroinflammation (NI) of the central nervous system. A twelve-amino acid peptide that transcytoses the BBB, termed MTfp,...
5.
McIntyre W, Healey J, Bhatnagar A, Wang P, Gordon J, Baranchuk A, et al.
Europace . 2019 Jul; 21(8):1159-1166. PMID: 31292622
Aims: To evaluate the efficacy and safety of vernakalant for the cardioversion of atrial fibrillation (AF). Methods And Results: We reviewed the literature for randomized trials that compared vernakalant to...
6.
Gordon J, Noble J, Midha A, Derakhshan F, Wang G, Adomat H, et al.
Cancer Res . 2019 May; 79(13):3320-3331. PMID: 31064850
Aberrant cholesterol metabolism is increasingly appreciated to be essential for prostate cancer initiation and progression. Transcript expression of the high-density lipoprotein-cholesterol receptor scavenger receptor B1 (SR-B1) is elevated in primary...
7.
Gordon J, Buonerba C, Pond G, Crona D, Gillessen S, Lucarelli G, et al.
Oncotarget . 2018 May; 9(28):19861-19873. PMID: 29731989
Background: Statins may potentiate the effects of anti-hormonal agents for metastatic castration-resistant prostate cancer (mCRPC) through further disruption of essential steroidogenic processes. We investigated the effects of statin use on...