Jacek Scianowski
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Explore the profile of Jacek Scianowski including associated specialties, affiliations and a list of published articles.
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19
Citations
68
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Recent Articles
1.
New insights in the mechanism of the SARS-CoV-2 M inhibition by benzisoselenazolones and diselenides
Sancineto L, Mangiavacchi F, Dabrowska A, Pacula-Miszewska A, Obieziurska-Fabisiak M, Scimmi C, et al.
Sci Rep
. 2024 Oct;
14(1):24751.
PMID: 39433805
Although global vaccination campaigns alleviated the SARS-CoV-2 pandemic in terms of morbidity and mortality, the ability of the virus to originate mutants may reduce the efficacy of vaccines, posing a...
2.
Laskowska A, Pacula-Miszewska A, Obieziurska-Fabisiak M, Jastrzebska A, Dlugosz-Pokorska A, Gach-Janczak K, et al.
Molecules
. 2024 Jun;
29(12).
PMID: 38930931
A series of phenyl -carbonyl selenides with o-ester functionality substituted on the oxygen atom with chiral and achiral alkyl groups was synthesized. All compounds are the first examples of this...
3.
Rakowiecki M, Studzinska S, Scianowski J, Bosiak M, Wolan A, Budny M
RSC Adv
. 2024 May;
14(23):15848-15855.
PMID: 38756849
A synthetic approach to ten metabolites of iodosulfuron-methyl sodium and metsulfuron-methyl was performed and reported in this study. The compounds of interest were prepared by controlled hydrolytic degradation of active...
4.
Liang X, Pacula-Miszewska A, Vartak R, Prajapati M, Zheng H, Zhao C, et al.
Curr Issues Mol Biol
. 2024 Mar;
46(3):2480-2496.
PMID: 38534773
In the present work, we evaluated the antifungal activities of two novel ebselen analogs, -allyl-benzisoselenazol-3(2H)-one (-allyl-bs) and -3-methylbutylbenzisoselenazol-3(2H)-one (-3mb-bs). Colorimetric and turbidity assays were performed to determine the minimum inhibitory...
5.
Laskowska A, Pacula-Miszewska A, Obieziurska-Fabisiak M, Jastrzebska A, Dlugosz-Pokorska A, Gach-Janczak K, et al.
Materials (Basel)
. 2024 Feb;
17(4).
PMID: 38399148
A series of unsymmetrical phenyl -carbonyl selenides with -amido function substituted on the nitrogen atom with chiral alkyl groups was obtained. The compounds form a series of enantiomeric and diastereomeric...
6.
Pacula-Miszewska A, Obieziurska-Fabisiak M, Jastrzebska A, Dlugosz-Pokorska A, Gach-Janczak K, Scianowski J
Pharmaceuticals (Basel)
. 2023 Nov;
16(11).
PMID: 38004426
Organoselenium compounds are well-known for their numerous biocapacities, which result from the uniqueness of the selenium atom and the possibility of constructing heterorganic molecules that can mimic the activity of...
7.
Liang X, Pacula-Miszewska A, Obieziurska-Fabisiak M, Vartak R, Mao G, Patel K, et al.
Molecules
. 2023 Nov;
28(21).
PMID: 37959796
In the present work, a series of -terpenyl organoselenium compounds (CHB1-6) were evaluated for antimycotic activity by determining the minimum inhibitory concentration (MIC) for each compound in fluconazole (FLU)-sensitive (S1)...
8.
Laskowska A, Pacula-Miszewska A, Obieziurska-Fabisiak M, Jastrzebska A, Gach-Janczak K, Janecka A, et al.
RSC Adv
. 2023 May;
13(21):14698-14702.
PMID: 37197685
Organoselenium compounds are well-known for their unique biological properties, including antioxidant, anticancer and anti-inflammatory. They result from the presence of a particular Se-moiety enclosed in a structure that provides physicochemical...
9.
Andrusiak J, Mylkie K, Wysocka M, Scianowski J, Wolan A, Budny M
RSC Adv
. 2022 Apr;
11(46):28934-28939.
PMID: 35478583
A six-step synthesis of xanthohumol (1a) and its d-derivative (1b) from easily accessible naringenin is reported. The prenyl side chain was introduced by Mitsunobu reaction followed by the europium-catalyzed Claisen...
10.
Laskowska A, Pacula-Miszewska A, Dlugosz-Pokorska A, Janecka A, Wojtczak A, Scianowski J
Materials (Basel)
. 2022 Mar;
15(6).
PMID: 35329523
A series of new chiral benzisoselenazol-3(2)-ones and their corresponding diselenides bearing an -amido function substituted on the nitrogen atom with various aliphatic and aromatic moieties were synthesized. All derivatives representing...