Jaap D van Buul
Overview
Explore the profile of Jaap D van Buul including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
116
Citations
3057
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Daniel A, van der Meer W, Wester L, de Waard V, van den Biggelaar M, van Buul J
Small GTPases
. 2023 Aug;
14(1):45-54.
PMID: 37528624
The RhoGEF Trio is a large multi-domain protein and an activator of the small GTPases Rac1, RhoG, and RhoA. Although Trio has been implicated in many cellular mechanisms like leukocyte...
12.
Mahlandt E, Palacios Martinez S, Arts J, Tol S, van Buul J, Goedhart J
Elife
. 2023 Jul;
12.
PMID: 37449837
The inner layer of blood vessels consists of endothelial cells, which form the physical barrier between blood and tissue. This vascular barrier is tightly regulated and is defined by cell-cell...
13.
Block J, Rashkova C, Castanon I, Zoghi S, Platon J, Ardy R, et al.
N Engl J Med
. 2023 Jun;
389(6):527-539.
PMID: 37342957
Background: Increasing evidence links genetic defects affecting actin-regulatory proteins to diseases with severe autoimmunity and autoinflammation, yet the underlying molecular mechanisms are poorly understood. Dedicator of cytokinesis 11 (DOCK11) activates...
14.
van Steen A, Gronloh M, Joosten S, van Alphen F, van den Biggelaar M, Nolte M, et al.
J Immunol
. 2023 Jun;
211(3):377-388.
PMID: 37341500
The endothelial lining of blood vessels is covered with a thin polysaccharide coat called the glycocalyx. This layer of polysaccharides contains hyaluronan that forms a protective coat on the endothelial...
15.
Gronloh M, Arts J, Palacios Martinez S, van der Veen A, Kempers L, van Steen A, et al.
EMBO Rep
. 2022 Nov;
24(1):e55483.
PMID: 36382783
Upon inflammation, leukocytes leave the circulation by crossing the endothelial monolayer at specific transmigration "hotspot" regions. Although these regions support leukocyte transmigration, their functionality is not clear. We found that...
16.
Morsing S, Zeeuw van der Laan E, van Stalborch A, van Buul J, Kapur R, Vlaar A
Transfusion
. 2022 Aug;
62(10):1961-1966.
PMID: 36004763
Background: Transfusion-Related Acute Lung Injury (TRALI) is a life-threatening complication of blood transfusions characterized by pulmonary endothelial cell damage and edema, with a high incidence in critically ill patients. The...
17.
Klanderman R, Bosboom J, Veelo D, Roelofs J, de Korte D, van Bruggen R, et al.
Sci Rep
. 2022 Jul;
12(1):12127.
PMID: 35840620
Transfusion-associated circulatory overload (TACO) is the leading cause of transfusion related morbidity and mortality. The only treatment is empirical use of furosemide. Our aim was to investigate if furosemide can...
18.
Schoppmeyer R, van Buul J
STAR Protoc
. 2022 Jul;
3(3):101509.
PMID: 35776649
This protocol presents an assay for transmigration analysis of human cytotoxic T cells (CTL) under physiological flow in vitro. We describe detailed analysis steps of human CTL behavior, from adhesion...
19.
Jeucken K, van Rooijen C, Kan Y, Kocken L, Jongejan A, van Steen A, et al.
Front Immunol
. 2022 Jun;
13:860327.
PMID: 35769477
Endothelial cells (ECs) are important contributors to inflammation in immune-mediated inflammatory diseases (IMIDs). In this study, we examined whether CD4 memory T (T) cells can drive EC inflammatory responses. Human...
20.
Morsing S, Zeeuw van der Laan E, van Stalborch A, van Buul J, Vlaar A, Kapur R
Physiol Rep
. 2022 Apr;
10(8):e15271.
PMID: 35439361
Acute respiratory distress syndrome (ARDS) is a major clinical problem without available therapies. Known risks for ARDS include severe sepsis, SARS-CoV-2, gram-negative bacteria, trauma, pancreatitis, and blood transfusion. During ARDS,...