Jos van Rijssel
Overview
Explore the profile of Jos van Rijssel including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
707
Followers
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Recent Articles
1.
Rademakers T, Manca M, Jin H, Orban T, Perisic L, Frissen H, et al.
Angiogenesis
. 2024 May;
27(3):461-474.
PMID: 38780883
The presence of atherosclerotic plaque vessels is a critical factor in plaque destabilization. This may be attributable to the leaky phenotype of these microvessels, although direct proof for this notion...
2.
Kempers L, Driessen A, van Rijssel J, Nolte M, van Buul J
Int J Mol Sci
. 2021 Sep;
22(18).
PMID: 34576329
Many cellular processes are controlled by small GTPases, which can be activated by guanine nucleotide exchange factors (GEFs). The RhoGEF Trio contains two GEF domains that differentially activate the small...
3.
Arts J, Mahlandt E, Gronloh M, Schimmel L, Noordstra I, Gordon E, et al.
Elife
. 2021 Aug;
10.
PMID: 34431475
Upon inflammation, leukocytes rapidly transmigrate across the endothelium to enter the inflamed tissue. Evidence accumulates that leukocytes use preferred exit sites, alhough it is not yet clear how these hotspots...
4.
Arts J, Mahlandt E, Schimmel L, Gronloh M, Niet S, Klein B, et al.
Front Immunol
. 2021 Jun;
12:667213.
PMID: 34084168
An inflammatory response requires leukocytes to migrate from the circulation across the vascular lining into the tissue to clear the invading pathogen. Whereas a lot of attention is focused on...
5.
Rademakers T, Goedhart M, Hoogenboezem M, Garcia Ponce A, van Rijssel J, Samus M, et al.
Haematologica
. 2020 Dec;
105(12):2746-2756.
PMID: 33256374
Bone marrow endothelium plays an important role in the homing of hematopoietic stem and progenitor cells upon transplantation, but surprisingly little is known on how the bone marrow endothelial cells...
6.
Klems A, van Rijssel J, Ramms A, Wild R, Hammer J, Merkel M, et al.
Nat Commun
. 2020 Oct;
11(1):5319.
PMID: 33087700
Arterial networks enlarge in response to increase in tissue metabolism to facilitate flow and nutrient delivery. Typically, the transition of a growing artery with a small diameter into a large...
7.
Stanicek L, Lozano-Vidal N, Bink D, Hooglugt A, Yao W, Wittig I, et al.
Commun Biol
. 2020 May;
3(1):265.
PMID: 32457386
Blood vessels are constantly exposed to shear stress, a biomechanical force generated by blood flow. Normal shear stress sensing and barrier function are crucial for vascular homeostasis and are controlled...
8.
Verstegen N, Unger P, Walker J, Nicolet B, Jorritsma T, van Rijssel J, et al.
Front Immunol
. 2019 Apr;
10:415.
PMID: 30930895
Growing evidence indicate that large antigen-containing particles induce potent T cell-dependent high-affinity antibody responses. These responses require large particle internalization after recognition by the B cell receptor (BCR) on B...
9.
Schimmel L, van der Stoel M, Rianna C, van Stalborch A, de Ligt A, Hoogenboezem M, et al.
Cell Rep
. 2018 Sep;
24(12):3115-3124.
PMID: 30231995
Leukocytes follow the well-defined steps of rolling, spreading, and crawling prior to diapedesis through endothelial cells (ECs). We found increased expression of DLC-1 in stiffness-associated diseases like atherosclerosis and pulmonary...
10.
Eelen G, Dubois C, Cantelmo A, Goveia J, Bruning U, DeRan M, et al.
Nature
. 2018 Aug;
561(7721):63-69.
PMID: 30158707
Glutamine synthetase, encoded by the gene GLUL, is an enzyme that converts glutamate and ammonia to glutamine. It is expressed by endothelial cells, but surprisingly shows negligible glutamine-synthesizing activity in...